New Possibilities of Diagnostics of Non-Alcoholic Fatty Liver Disease
Journal Title: Current Trends in Gastroenterology and Hepatology - Year 2018, Vol 1, Issue 3
Abstract
The aim of the study was to create a non-invasive model for diagnosing fibrosis and steatosis in non-alcoholic fatty liver disease. Materials and methods. The study included 183 patients with liver steatosis according to ultrasound of the liver. General clinical examination, verification of the stage of fibrosis and steatosis of the liver on the Fibroscan 502 TOUCH device with the CAP software was carried out. Results of the study. Fibrosteatotest ©, based on stigmas of inflammation activity, insulin resistance, lipid spectrum for the diagnosis of fibrosis and steatosis (diagnostic accuracy of more than 80% compared to the results of fibroscanning), is created by the method of discriminant analysis, which allows to identify patients with the 2nd and more stage of fibrosis and steatosis of the liver, who need medication. Conclusions: The Fibrosteatotest © test allows for screening patients to identify the stages of fibrosis and steatosis of the liver that require drug therapy.
Authors and Affiliations
Pirogova I Yu, Yakovleva SV, Neuimina Tatyana Valeryevna, Sinitsyn SP, Chulkov VS, Shamaeva Tatyana Nikolaevna
Keywords
Related Articles
- EP ID EP569996
- DOI 10.32474/CTGH.2018.01.000111
- Views 49
- Downloads 0
Portal Hypertensive Gastric Polyps
Portal hypertension is associated with an increased number of gastric polyps, hence the term portal hypertension-associated gastric polyps. Histopathological examination reveals mucosal hyperplasia and vascular prolifera...
The Current Approach to the Hepatocellular Carcinoma; A Mini Review of Etiology, Prognosis and Treatment
Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and is one of the major causes of cancerrelated deaths. HCC is reported to be the second most fatal malignancy. The major risk factors for HCC...
Primary Liver Cancer in Adults
Liver cancer includes two main types: hepatocellular carcinoma (HCC) and intrahepatic bile duct cancer. Incidence and mortality. Calculation of the number of new cases and deaths due to liver and intrahepatic bile duct...
Reflections About the Gut, A Microbiologist’s Perspective
Without doubt, the original function of the human gut was to digest and absorb food. Its epithelial cells absorb food after it has been processed to smaller components by enzymatic digestion. Comparable epithelial proces...
Eradication Failure of Helicobacter Pylori Among Children’s Population
Helicobacter pylori (H. pylori) is a Gram-negative bacterium responsible for the development of gastritis that may further progress to more severe conditions, peptic ulcer disease and gastric cancer [1,2]. H. pylori have...