NON-OPERATIVE MANAGEMENT OF PERFORATED GASTRODUODENAL ULCER- A PROSPECTIVE OBSERVATIONAL STUDY IN A RURAL TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 5
Abstract
BACKGROUND Perforation remains a major life-threatening complication of peptic ulcer disease. Morbidity and mortality following perforated peptic ulcer remains substantial. MATERIALS AND METHODS A prospective study of the outcome of non-operative treatment of patients of perforated peptic ulcer was conducted for a period of 2009 to 2014. Patients with clinical and radiological diagnosis of perforated peptic ulcer were included for conservative management consisting of intravenous fluid, nasogastric suction, antibiotics and proton pump inhibitor (Omeprazole). RESULTS Four (04) of these 26 patients did not improve after 12 hours of conservative management and required an operation. There is no mortality in this conservative management group and morbidity is 4%. Median hospital stay was 10 days. CONCLUSION The non-operative management of perforated peptic ulcer in the era of proton pump inhibitor may be possible in selected patients, provided strict guidelines are followed
Authors and Affiliations
Dipan Mukhopadhyay, Partha Sarathi Dutta
Keywords
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- EP ID EP368783
- DOI 10.14260/jemds/2018/147
- Views 93
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