NOVEL CHITOSAN DERIVATIVES AS FILMS WITH AN ANTIMICROBIAL EFFECT
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2013, Vol 0, Issue
Abstract
This paper presents the results of chitosan acylation with linoleic (LA) and dilinoleic acid (DLA). The chemical structures of the new derivatives with different degrees of substitution of LA and DLA were assessed by Fourier transform infrared spectroscopy. Polymer films were prepared by solution casting and drying. The resistance of films to bacterial degradation was tested according ISO 846 standard: “Plastic-Evaluation of the Action of Microorganisms” and the antimicrobial properties were assessed using Gram-negative bacterium Escherichia coli and the fungi Candida albicans in an agar diffusion test. Bioassays showed an antimicrobial effect in direct contact with the material.
Authors and Affiliations
Agata Niemczyk, Mirosława El Fray
NOVEL CHITOSAN DERIVATIVES AS FILMS WITH AN ANTIMICROBIAL EFFECT
This paper presents the results of chitosan acylation with linoleic (LA) and dilinoleic acid (DLA). The chemical structures of the new derivatives with different degrees of substitution of LA and DLA were assessed by Fou...
HETEROGENEOUS DEACETYLATION OF CHITIN DEGRADED WITH HYDROGEN PEROXIDE IN A MICROWAVE FIELD
Two-step procedure of obtaining chitosan with tailored properties has been elaborated. In the first step chitin from the shells of krill (Euphausia superba) and common shrimp (Crangon crangon [L.]) was subjected simultan...
METHOD FOR PREPARATION OF HYBRID SPHERICAL CHITOSAN/POLY(LACTIC ACID) STRUCTURES
The novelty of preparation is combining two biopolymers into one hybrid system to obtain desired release kinetics of active substances. The substance can be enclosed in the porous PLA microspheres or in the chitosan matr...
CHITOSAN/POLY(VINYL ALCOHOL) HYDROGELS AS CONTROLLED DRUG DELIVERY SYSTEMS
In order to achieve hydrogel and drug release profiles, a comprehensive knowledge of the types, properties and syntheses of hydrogel polymer networks are needed. For this reason, a natural biopolymer hydrogel based on ch...
ASSESSMENT OF PHARMACEUTICAL PROPERTIES OF GYNAECOLOGICAL HYDROPHILIC GELS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN
Gels containing lactic acid complexed with chitosan at a stoichiometric ration 1:1 and 2:1 and 5-25% content of polyoxyethylene glycol 200 are able to move from 25 to 30 cm. The addition of glycerol increases the movabil...