NOVEL FORMULATION STRATEGIES FOR INSULIN DELIVERY
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 2
Abstract
Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Successful oral insulin delivery involves overcoming the enzymatic and physical barriers. Several companies across the globe are developing oral insulin based on different technology platforms. Insulin has been encapsulated in nanoparticles by mucoadhesive polymers such as chitosan, poly (lacticco-glycolic acid) (PLGA), and alginate which prevent enzymatic degradation and allow absorption across the epithelial layer in Peyer’s patches.
Authors and Affiliations
Dhruvkumar Soni
BRINE SHRIMP LETHALITY BIOASSAY OF BOUGAINVILLEA GLABRA
The crude methanolic extract of Bougainvillea glabra leaves has been investigated for the evaluation of the cytotoxic activity. All the extracts of the plant were screened for their cytotoxicity by using brine shrimp nau...
SOLUBILITY ENHANCEMENT OF EFAVIRENZ (BCS CLASS II DRUG) BY CYCLODEXTRIN INCLUSION COMPLEX TECHNIQUE
The solubility of BCS class II drugs can be enhanced using inclusion complex techniques. Cyclodextrin (CD) and its derivatives are promising carrier for the enhancement of aqueous solubility of drugs. The use of the Knea...
WOUND HEALING POTENTIAL OF GRANDIFLORENIC ACID ISOLATED FROM WEDELIA TRILOBATA LINN.
The ethyl acetate fraction from ethanolic extract of W. trilobata leaves displayed antibacterial and fibroblast stimulatory activities thereby suggesting potential wound healing properties. Ethyl acetate fraction was fur...
AN OVERVIEW OF ANALYTICAL INSTRUMENT QUALIFICATION WITH REFERENCE OF PHARMACEUTICAL INDUSTRY
In the most general sense, validation refers to a process that consists of at least four distinct components or steps: software, instruments, methods or procedures, and system suitability The system, the software, and th...
ELUCIDATING THE STRUCTURAL REQUIREMENTS OF NOVEL PAZOPANIB DERIVATIVES TOWARDS TYROSINE KINASE INHIBITORY ACTIVITY THROUGH CLASSICAL HANSCH AND DE-NOVO APPROACH
Quantitative structure–activity relationship (QSAR) and Molecular modeling study have been performed on a series of novel Pazopanib derivatives by using the Mixed Hansch Fujita-Ban approach and employing AM1 calculations...