Novel Transfusion parameters in Blood bank for Thalassemia patients
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Thalassemia major is most common monogenic disorder in the world. Around 1,00,000 children are born each year with the severe b homozygous state of the disease in India. The objectives of this study was to assess clinical data and novel transfusion parameters of Thalassemia major patients attending tertiary care hospital. This was undertaken as very few studies have been done in this region of the country. Materials and Method: The study was done at a tertiary care teaching hospital from January 2014 to December 2014. 35 thalassemia major patients who received blood transfusions in the hospital were taken as inclusion. Clinical details, blood transfusion details and novel parameters of transfusion annual blood requirement and its derivatives were collected on proforma for all patients and data interpreted. Result: Males (80%) outnumbered females (20%) with male to female ratio of 4:1. Nearly half of the study population was aged between 10 to 12 years (51.43). Majority of the patients had one blood transfusion per month (91.43%) and were on chelation therapy (71.43%). Novel transfusion parameters which includes Annual blood requirement, Mean Annual pure red cell requirement, Mean Annual iron load and Mean Daily iron loading were calculated for each patient. Conclusion: The present study describes the novel transfusion parameters in blood bank for thalassemia major patients attending the tertiary care hospital and emphasizes on maintenance of transfusion record of thalassemia major patients for better management of these patients.
Authors and Affiliations
Mallikarjun A. Pattanashetti, Ganga S. Pilli
Keywords
Related Articles
- EP ID EP315398
- DOI 10.18231/2394-6792.2017.0084
- Views 62
- Downloads 0
Clinicopathological study of ABO blood types in prostate cancer
Aim To study the association between the ABO blood groups and clinicopathological features in cases of prostate cancer PCaMaterials and Methods Fifty cases of PCa diagnosed on transurethral resection of prostate chips we...
Fine-needle aspiration cytology of granulocytic sarcoma: A cytomorphologic analysis
Introduction Granulocytic sarcoma is a rare extramedullary tumor comprising of immature myeloid cells in an extramedullary site which is commonly found with myeloid leukemia acute or chronic or occasionally with chronic...
Myeloid sarcoma of maxillary sinus
We report a case of isolated myeloid sarcoma MS of maxillary sinus in a patient who had no evidence of leukemia at the time of diagnosis of MS A 39 year old healthy woman presented with right cheek swelling of one year d...
Secondary renal amyloidosis complicating psoriatic arthropathy
Introduction Secondary AA amyloidosis is a classical complication of chronic inflammatory conditions like rheumatoid arthritis ankylosing spondylitis and inflammatory bowel disease or chronic infectious diseases like tub...
Clinicopathological correlation of ovarian tumors in a tertiary care hospital
Introduction and Objective Ovary is one of the complex organs in terms of its embryology histology steroidogenesis and tumor incidence The present study highlights the correlation between the clinical and pathological fe...