Solid Pseudo Papillary Tumor of Pancreas: An institutional experience
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Solid-pseudo papillary tumor (SPPT) of the pancreas is a very rare tumor and very few case studies has been published from India. Aims and Objectives: To evaluate the clinical presentations SPPT of pancreas and to discuss the treatment, radiological, histopathological and immunohistochemical (IHC) findings with cytogenetic work up and subsequent follow up of the patients. Materials and Method: We retrospectively reviewed the six patients with SPPT managed in our hospital between 2008 to 2016. All the six cases were noted in females and their age ranges from 15 to 25 years. The clinical diagnosis were confirmed with ultrasound and computerized tomography. Distal Pancreatectomy along with splenectomy in two cases and Whipple’s procedure was performed in other four cases. Cytogenetic workup was done in two cases. Results: The tumors were large, well encapsulated with mean diameter of 7 cm’s, had solid and cystic areas and were distributed in head, body and tail of pancreas. IHC findings revealed tumors, positive for neuron specific enolase, cytokeratin, progesterone, vimentin and focal positivity for chromogranin, and synaptophysin. The follow up of the patient revealed pseudo cyst of pancreas in one case. Cytogenetic work up revealed derivatives of 17th, 13th, 9th chromosomes. Conclusion: SPPT is a rare tumor with good prognosis after surgical resection.
Authors and Affiliations
E. Jaya Shankar, C. Nalini Mohan, T. Sujatha, G. Satyanarayana, AK Deshpande
Keywords
Related Articles
- EP ID EP315481
- DOI 10.18231/2394-6792.2017.0090
- Views 43
- Downloads 0
Clinicopathological and immunohistological profile of infiltrating ductal carcinoma breast in a tertiary care centre of western UP- A study of 100 cases
Introduction Breast cancer is the most common cause of death of women worldwide and it is the most common malignancy in Indian females followed by carcinoma cervix Diagnosis involves various modalities like clinical exam...
Spectrum of papillary lesions of breast with immunohistochemistry and review of literature
Background: Papillary lesions of breast are very rare. They are classified as benign, borderline and malignant. Benign papillary lesions constitute less than 10% of all benign lesions of the breast and malignant papillar...
Core needle biopsy verses fine needle aspiration cytology in palpable breast lesions- a comparative study
Background: Cytological diagnosis has its own limitations specially in suspicious lesions and poorly circumscribed lesions in Breast. Core needle biopsy (CNB) emerged as an important tool in assessment of breast lesion w...
Study of paediatric renal biopsies with clinicopathologic correlation and comparison with literature on adult renal biopsies
Introduction Renal biopsy is frequently used in complete workup for renal diseases The kidney reacts in a limited number of patterns to various injuries and the clinical manifestations corresponding to these reactions ar...
Orbital Rhabdomyosarcoma with anaplastic features
Orbital rhabdomyosarcoma (RMS) is the most common orbital malignancy of childhood. It is a highly malignant tumour and is one of the few life threatening diseases, if its diagnosis is delayed. Among the entire group of e...