Nuclear anomalies in the buccal cells of children under dental treatment
Journal Title: RSBO - Year 2011, Vol 8, Issue 2
Abstract
Introduction: Since some dental materials may be aggressive to a person’s body, studies involving such materials seem to be necessary. Objective: This study was conducted to evaluate the genotoxicity of dental materials through micronucleus (MN) test. Material and methods: Exfoliated buccal cells of 4-to-12 year-old children, who were on some type of dental treatment, were collected either before or after the treatment ending. Each sample was composed of 1,000 cells per patient. Student’s t test was used for comparison. Results: The dental materials were divided into 3 groups, as follows: cement, monomers, and their combination. Treatments using monomer + cement-based materials were found to increase significantly the number of binucleated (BN) cells, (p < 0.05) which indicate several degenerative nuclear changes. Conclusion: The combination of cement-based dental material with monomers increases the cytotoxic action of dental materials.
Authors and Affiliations
Elisângela Rezende, Maria Mendes Costa, Johnson Fonseca, Alex Ribeiro
Keywords
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