Omics technology: an important tool in mechanism studies of Chnese herbal formulas

Journal Title: Traditional Medicine Research - Year 2021, Vol 6, Issue 1

Abstract

Identifying the active ingredients from natural herbal medicines and demonstrating their potential mechanisms are key points in the traditional Chinese medicine (TCM) field. In recent years, increasing studies have focused on the effects and mechanisms of Chinese herbal formulas. Basic studies on these formulas further coincide with the theory and practical use of TCM according to the clinical experiences for thousands of years. Single compounds have specific molecular structures; therefore, their methodologies in effect and mechanism studies are similar in both Western and Eastern medicines, making them more acceptable by researchers worldwide. On the contrary, the multicomponent, multitarget, and multipathway structures of Chinese formulas make it challenging to explore their mechanisms accurately where the routine method used in Western medicine studies would be inapplicable, which is the main reason for the unacceptance of Chinese herbal formulas by researchers worldwide and presents a huge obstacle to the modernization of TCM. With the rapid progress in basic TCM studies, scientific and technological innovations have achieved a breakthrough in TCM.

Authors and Affiliations

Huan-Tian Cui,Lu Yang,Yu-Ting Li,Hong-Wu Wang

Keywords

Related Articles

Systematic analysis of components and contents in Houttuynia cordata Thunb

Objective: This study aims to provide the material basis for the molecular mechanism of Yuxingcao (Houttuynia cordata Thunb, HCT) through the method of evidence-based study to summarize the natural constituents isolated...

News and Comments: Have Phase Ⅲ clinical trials of Compound Danshen Dripping Pill “tragically failed”?

Compound Danshen Dripping Pill (CDDP) is the traditional Chinese medicine that has been widely used in China for the treatment of diseases such as coronary heart disease, stenocardia, and myocardial ischemia. The applica...

Two Empirical Formula for Hemostasis

Zhixue San Jin Yin Hua (Flos Lonicerae) 75g, Sheng Di (Radix Rehmanniae Recens) 75g,Bai Ji (Rhizoma Bletillae) 75g, Ma Bo (Lasiosphaera seu Calvatia) 75g, Er Cha (Catechu) 37g, Xue Jie (Sanguis Draconis)37g, Xue Yu Tan (...

A systematical review of traditional Ayurvedic and morden medical perspectives on Ghrita (clarified butter): a boon or bane

Highlights Ghrita (clarified butter), treated as the culprit of a number of diseases, has been depicted incorrectly for a long time. This review presents the complete picture in view of Ayurvedic perspective and recen...

Metabonomics/metabolomics analysis technology and its application in quality control of traditional Chinese medicines

This article systematically addresses metabolomics/metabonomics techniques and examples of their use in evaluation of traditional Chinese medicines. It provides a new reference for Chinese medicines and the identificatio...

Download PDF file
  • EP ID EP690505
  • DOI 10.12032/TMR20200920199
  • Views 151
  • Downloads 0

How To Cite

Huan-Tian Cui, Lu Yang, Yu-Ting Li, Hong-Wu Wang (2021). Omics technology: an important tool in mechanism studies of Chnese herbal formulas. Traditional Medicine Research, 6(1), -. https://europub.co.uk/articles/-A-690505