One-pot route to nitriles from aldehyde and hydroxylamine hydrochloride on silica-gel
Journal Title: Asian Journal of Green Chemistry - Year 2018, Vol 2, Issue 4
Abstract
A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.
Authors and Affiliations
Rakesh Ranjan Chakraborty, Pranab Ghosh
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