Organ Bioengineering, Regeneration and Repair: Where the Future of Organ Transplantation is Taking Shape

Journal Title: Journal of Transplantation & Stem Cell Biology - Year 2014, Vol 1, Issue 1

Abstract

Although organ transplantation is now widely viewed as one of the monumental achievements in the history of modern medicine, that was not always the case. Indeed, back at the beginning of the 20th century the idea of replacing diseased organs with new functioning counterparts seemed unthinkable. However, as a result of the vision and perseverance of pioneers, their temerity to challenge ethical and biological paradigms, concomitant progress in surgical techniques and know-how, along with the conception, implementation and development of technologies and the creation of ad hoc infrastructures, the dream eventually became reality and organ transplantation has become routine medical practice. Patients that would have inexorably been destined to death prior to these advances can now have their damaged organs replaced and enjoy a satisfactory quality of life, quite comparable to that of non-transplant individuals.

Authors and Affiliations

Giuseppe Orlando, Stephen J. Walker

Keywords

Related Articles

First Results on Three Patients Treated with Topical Recombinant Human Erythropoietin (rhEPO) to Improve Wound Healing in Diabetic Foot Ulcers

Chronic wounds not only induce individual distress but also cause enormous and rapidly growing costs for our health care systems and society in general. The fastest growing groups of chronic wounds are Diabetic Foot Ulce...

Scaffold Free 3D Culture of Mesenchymal Stem Cells; Implications for Regenerative Medicine

Mesenchymal stem cells (MSCs) are recognized as important sources for regenerative medicine (RM). Adherent cultures, long time considered definitory for MSCs phenotype, are relatively easy to perform and to assess. Two d...

Stem Cell Therapies in Regenerative Medicine and Diabetes Mellitus: Advances, Constraints and Future Prospects

Stem cell therapy is one of the most promising treatments for the near future. This kind of therapy can ameliorate or even reverse some diseases and have potential applications in regenerative and replacement medicines a...

Regulation of Hypoxia-Induced Cell Death and Application of Hypoxic Preconditioning to Stem Cell Transplantation

Hypoxia is a commonly encountered feature of the cellular microenvironment in a number of processes in which programmed cell death (apoptosis) affects disease progression. These diseases include myocardial infarction, st...

Cognitive Changes after Cellular Therapy in a Case of Intellectual Disability

Intellectual Disability (ID) is a developmental disability characterized by sub average intellectual functioning, occurring in 2-3% of the population. The underlying cause in ID is the sub-functioning of the neurons whic...

Download PDF file
  • EP ID EP207555
  • DOI 10.13188/2374-9326.1000005
  • Views 122
  • Downloads 0

How To Cite

Giuseppe Orlando, Stephen J. Walker (2014). Organ Bioengineering, Regeneration and Repair: Where the Future of Organ Transplantation is Taking Shape. Journal of Transplantation & Stem Cell Biology, 1(1), 1-2. https://europub.co.uk/articles/-A-207555