ОСОБЛИВОСТІ МЕТАБОЛІЗМУ КІСТКОВОЇ ТКАНИНИ У ПАЦІЄНТІВ ІЗ ХВОРОБОЮ ПАРКІНСОНА ТА СИСТЕМНИМ ОСТЕОПОРОЗОМ
Journal Title: INTERNATIONAL ACADEMY JOURNAL "Web of Scholar" - Year 2018, Vol 1, Issue 9
Abstract
The aim of this study was to evaluate the bone metabolism peculiarities in patients with Parkinson's disease (PD) and osteoporosis. We performed a cross-sectional study of 34 patients with PD and 34 age-matched controls with primary osteoporosis. The diagnosis of osteoporosis in both groups was confirmed by dual-energy X-ray absorptiometry. It was found that patients with PD had significantly lower serum vitamin D and phosphorus levelsthan that in controls. In the PD group bone formation (P1NP) and resorption (β-CTx) markers were in 2 and 1.7 times higher versus controls. Our findings support the hypothesis that low bone mineral density in patients with PD is the results of osteoporosis and osteomalacia.
Authors and Affiliations
М. А. Бистрицька, Н. І. Балацька, Т. Ю. Солоненко
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