Outcome of Induction of Labour by Oral Misoprostol of Intrauterine Fetal Death
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 10
Abstract
Objective: To review our one year experience in induction of labor in cases of intrauterine fetal death (IUFD) using oral misoprostol. Methods: A descriptive study of 170 women with IUFD after 28 weeks who had induction of labor with oral misoprostol at the obstetric unit of our BRIMS Hospital, Bidar. Results: 169 patients were delivered vaginally. Misoprostol dose ranging from 25 to 300 µg was used to achieve labor. Majority (65%) of the patients required a total dose of 100 µg or less to achieve labor. The dose required to achieve labor was found to decrease with increasing gestation; 50 µg at 36 weeks and above and 200 µg at between 28 and 30 weeks. The induction delivery interval (IDI) varied from 4 hours to 36 hours with a mean of 15 hours ± 5 hours. The IDI was also found to be dependent on gestational age. Of the 145 (85.0%) that delivered within 24 hours, 125 (73.53%) were at least 32 weeks. Fifteen (8.8%) women required augmentation. Fifteen (8.8%) patients had post partum haemorrhage because of retained bits of membranes. Three (1.7%) patients had retained placenta. One (0.5%) patient had rupture uterus. Conclusion: The results of this study confirm that misoprostol is an effective induction agent in IUFD, but it should be used with caution and strict monitoring. It should not be given by paramedical staff.
Authors and Affiliations
Uma Deshmukh, Meenal Vardhan
Keywords
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