Outcome of Vitamin D Supplementation on Implant Osseointegration in Patients Suffering from Chronic Kidney Disease: A Prospective Randomized Study
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2016, Vol 6, Issue 7
Abstract
Aim This study was aimed to investigate the effect of Vit D supplementation on implant osseointegration in CKD. Settings and Design This was a prospective randomized study conducted on 20 patients with complaint of missing teeth and who had chronic kidney disease. After evaluation of the medical reports of the patients; medical consultancy was taken from the physician. Materials and Methods Out of twenty patients ten were given vitamin D supplements (60,000 IU). Implants were placed under aseptic conditions. The following radiographic and clinical parameters were evaluated-1) Height of crestal bone. 2) Implant mobility. 3) Papilla fill index. 4) bleeding on probing. Statistical Analysis Used The results were compiled and statistically analyzed using SPSS Version 19 Version. The Mann–Whitney U Test was used for the intergroup comparison and Wilcoxon Sign Rank Test for the intra-group comparison. Results Statistically, significant results were seen in Group I, which were on vitamin D supplementation in relation to osseointegration when compared to group II. It demonstrated that weekly supplementation with 60,000 IU of cholecalciferol for 12 weeks is an effective way of correcting vitamin D status in patients with CKD stage 3 and 4 which also, helps in the formation of bone for osseointegration. Conclusion Implants placed in patients with CKD on vitamin D supplementation were more successfully osseointegrated and functional, which was confirmed clinically and radiographically.
Authors and Affiliations
Preetinder Singh, Yash Paul Dev Sharma,, Raghav Yashbir, Kaur Manvir, Sharma Shivli, Wahi Ankur
Keywords
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