OXYTOCIN-LIKE EFFECT OF HARPAGOPHYTUM PROCUMBENS DC [PEDALIACEAE] SECONDARY ROOT AQUEOUS EXTRACT ON RAT ISOLATED UTERUS
Journal Title: African Journal of Traditional, Complementary and Alternative Medicines - Year 2006, Vol 3, Issue 1
Abstract
Harpagophytum procumbens DC [family: Pedaliaceae] is widely used in South African traditional medicine for the treatment, management and/or control of a variety of human ailments. Some traditional health practitioners of South Africa have claimed that H. procumbens secondary root is a useful obstetric remedy for induction or acceleration of labour, as well as for expulsion of retained placentas in pregnant women. In the present study, we have, therefore, examined the effects of Harpagophytum procumbens secondary root aqueous extract (HPE) on isolated uterine muscle strips taken from pregnant and non-pregnant, young female rats. The plant’s extract (HPE, 10–800 g/ml) induced concentration-related, significant (P
Authors and Affiliations
Ismail Mahomed, John Ojewole
Keywords
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