Pancytopenia - A Study on Clinical and Etiological Profile at a Tertiary Care Institute
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 1
Abstract
Introduction: Pancytopenia is a common hematological condition of varied etiology; however, only a few studies on pancytopenia from the northern regions of India have been published. Pancytopenia is the deficiency of all three cellular elements of blood, resulting in anemia, leucopenia, and thrombocytopenia. The frequency of underlying pathology causing pancytopenia varies considerably depending on various factors including age, geographic distribution, and genetic disturbances. Purpose: The purpose of the study was to evaluate the clinical and etiological profile of patients presenting with pancytopenia to a tertiary care hospital of northern India. Methods: A total of 66 patients were included in this study over a period of 18 months. Basic investigations were performed for each patient including hemoglobin, total leukocyte count, platelet count, and reticulocyte count. Absolute values including packed cell volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were calculated for every patient. Results: A total of 66 patients were studied over a period of 18 months including 40 males and 26 females. Male to female ratio was 1.53:1. The most common cause of pancytopenia was megaloblastic anemia (MA) found in 23 patients (34.84%), followed by aplastic anemia in 5 patients (7.57%), undiagnosed cases in 5 patients (7.57%), tuberculosis in 4 patients (6.06%), multiple myeloma and myelodysplastic syndromes in 3 (4.54%) patients each, respectively. Conclusion: MA is still the most common cause of pancytopenia in our setting. All patients with pancytopenia should be sought for MA as it is a potentially treatable condition.
Authors and Affiliations
Nadeem Ahmad, Nihida Akhter, Tufail Ahmad
Keywords
Related Articles
- EP ID EP478463
- DOI -
- Views 101
- Downloads 0
Profile of Burn Cases at a Tertiary Care Hospital in Goa, India
Introduction: Burn injury is an important public health problem and is largely preventable. Burn injuries could lead to lifelong disability and disfigurement. Most of these cases are reported from low- and middle-income...
Dysphonia Causative Diagnosis Linked to Voice Handicap Index of the Patients with Dysphonia
Background: Dysphonia has a negative impact not only on communication but also on the patients’ social and professional life. Detection of the underlying causes and the role of the predisposing factors in various conditi...
Prevalence of Deformities in Leprosy in Tertiary Care Center
Introduction: Deformities are the common complications of leprosy. This study enables us to find out the common types of deformities in tertiary care center so that an effective rehabilitation can be achieved. Aim: To fi...
Histopathological Study of Neoplastic and Non-neoplastic Lesions of the Ovary in Sanjay Gandhi Memorial Hospital/Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India
Introduction: Tumors of the ovary are common forms of neoplasms in women. In the developed world, ovarian carcinoma is the fourth or fifth most common cause of death from all cancers in women, and 7% of patients with the...
Prevalence of Refractive Errors among the School going Children at a Tertiary Center of West Bengal
Background: Refractive error is an avoidable cause of visual impairment. Diagnosis and treatment of refractive errors are not only simple but also the most effective forms of eye care. Aims and Objectives: To study the p...