Pediatric Primary Central Nervous System Lymphoma
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 7
Abstract
Introduction: Primary central nervous system lymphoma (PCNSL) is rare brain tumour in pediatric age group. Primary central nervous system lymphoma is an extra-nodal malignant tumour and is confined to brain, eyes, or leptomeninges. Case report: We report the case of PCNSL in a nine year old child who presented to M.M. Hospital with the history of fever since 20 days (on and off), swelling over face and eyes for 16 days, deviation of mouth for 16 days, headache and vomiting for 3 to 4 days and loss of appetite for 3 days. Magnetic resonance imaging of the brain revealed a large poorly defined soft tissue enhancing mass involving skull base centered in basisphenoid with small parenchymal lesion in left frontal region. Conclusion: Patient was managed with systemic chemotherapy in combination with radiotherapy. Intrathecal therapy reserved for cases with lymphomatous meningitis, and the role of ultra high dose therapy and stem cell rescue remain to be evaluated.
Authors and Affiliations
Gurmeet Singh, Aanchal Saini, Sonam Agrawal, Karan Shabad Singh Rekhi
Keywords
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