Pediatric Tumors Of Central Nervous System (CNS) – An Epidemiopathologic Research Study
Journal Title: International Journal of Medical and Health Sciences - Year 2012, Vol 1, Issue 3
Abstract
Background: Pediatric tumors of central nervous system (CNS) are 2nd most common tumors after Leukemia in children. Presentation of pediatric CNS tumors is different from adult CNS tumors. There is a diverse distribution of these tumors in children when compared to tumors in adults. Till today there are a very few published databases regarding the epidemiological profile of Pediatric CNS tumors in our country. Aim: To sketch the epidemiological picture of pediatric CNS tumors (<15 years) Objectives: To determine the incidence, age, sex, location, histopathologicalvariants and subtypesof pediatric CNS tumors and map the data with other epidemiological studies. Materials and methods: A review of 148 medical records diagnosed as CNS tumors was carriedout in various government and private hospitals in central and southern regions of Andhra Pradesh. Amongst which 50 (33.7%) cases werepediatric CNS tumors. A broad discriminativeretrospective study was done for a period of 3 years (2008-2011). Results: During the 3 years of the study period, 148 CNS tumors were noted in which 50 (33.7%) werepediatric CNS tumors. 48(96%) were intracranialand 2(4%) were intraspinaltumors. 36(72%) were male and 14(28%) were female. M:F ratio was 2.57:1. Thus, evident male predominance was observed. Majorityof cases were observedin age groupof 11-15 years and maximum number of cases was seen in individuals of 12 years old. The mean age at diagnosis was 9.02 and median agewas 9±4.07 years. 38(75%) were infratentorialand 12(25%) were supratentorialtumors. Astrocytomawas the most common tumor – 16(32%) cases. Among Astrocytoma – Pilocytic Astrocytoma was the common tumor – 8(50%) cases. Conclusion: Pediatric CNS tumors constitute a varied group with respect to incidence, distribution, anatomical location, histopathologicalvariants and subtypes. Thus, it is necessary to formulate separate lines of investigations and management aspects for different tumors in children for better care, treatment and prognostic evaluation.
Authors and Affiliations
Md K Faheem N, Jyothi V, B Syama SR
Keywords
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