Peritoneal dialysis in on malarial AKI children in a tertiary care centre hospital
Journal Title: Medpulse International Journal of Pediatrics - Year 2019, Vol 9, Issue 1
Abstract
Background: Peritoneal dialysis (PD) is the main stream of treatment as renal replacement therapy in pediatric patients with AKI in developing countries. Acute kidney injury (AKI) is a well-recognized complication of severe malaria in adults, but its incidence, prevalence and clinical importance in paediatric medicine not well documented.Objectives: To find out the effect of peritoneal dialysis on outcome of malarial AKI children in a tertiary care centre.Methods: A cross-sectional study done in under 14 children suffering from severe malaria (SM). Neonates, children with associated pre-existing renal disease or having chronic kidney disease (CKD) or acute on CKD and known hypertensives were excluded. All the enrolled children were screen for AKI as per KDIGO guidelines and categorised in two three stages. PD was done as per the predefined criteria and all relevant data were analysed with computer generated software.Results: Out of 203 SM cases, AKI detected in 14% with female predominance Mortality among renal failure patients is 26.96%. PD required in 51.0% of patients and mortality rate of 24.0% in KDIGO stage I, II but 53.0% in KDIGO Stage III significance (p=0.000). There is a significant correlation between pre-dialysisand post dialysis serum urea/ creatinine/ potassium/ TPC and urine output (p = <0.005).Conclusion: AKI is an under-recognized complication in young kids with SM and is related to enhance acute/ long-term morbidity and mortality. Its early detection and intervention by peritoneal dialysis improves the same.
Authors and Affiliations
Nagesh Dasarwar, Datla Sravya
Keywords
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