Pharmacological intervention of the fruit of plant Ananas comosus acting as hepatoprotective activity in animal models
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 3
Abstract
In the initial step of the project work various extracts of ripe fruits have been prepared by using successive extraction procedure and thus obtained extracts were subjected to preliminary phytochemical screening. Preliminary phytochemical tests have indicated the presence of tannins, triterpene and flavonoids in aqueous and ethanolic extracts. Similarly steroids are also present in petroleum ether and chloroform extracts of ripe fruits of Ananas comosus. Rats treated with alcohol developed a significant hepatic damage observed as elevated serum levels of hepatospecific enzymes like SGPT, SGOT and ALP when compared to normal control. Treatment with Silymarin had showed good protection against alcohol induced toxicity to liver. Groups treated with ethanolic and aqueous extracts of fruits of Ananas comosus showed significant effects.
Authors and Affiliations
Debashis Mallik, Chiranjib Bhattacharjee, T. Shivraj Gouda
Keywords
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