PHENYTOIN INDUCED TOXIC EPIDERMAL NECROLYSIS (TEN) IN AN ADULT
Journal Title: Stanley Medical Journal - Year 2015, Vol 2, Issue 3
Abstract
A 38 year old male patient was treated with paracetamol and phenytoin tablets for fever and convulsions. On the fourth day of treatment, he developed generalised erythema and blistering of skin. A provisional diagnosis of toxic epidermal necrolysis was made. Both the drugs were stopped and he was treated with i.v.fluids, antibiotics and steroids. He completely recovered in 15 days. Toxic epidermal Necrolysis (TEN) is a rare immune-mediated life-threatening reaction characterised by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and death. The possibility of occurrence of TEN with phenytoin must be kept in mind. Early diagnosis of the condition and proper treatment with steroids help in recovery.
Authors and Affiliations
J. Sam Anbu Sahayam, Vasanthira K. , Jeyalalitha R, Hemavathy G
Keywords
Related Articles
- EP ID EP217302
- DOI -
- Views 95
- Downloads 0
AMELANOTIC MELANOMA OF THE ANAL CANAL
Melanoma of the anal canal is a rare tumour that can present as a mass, pain or bleeding and/or can be amelanotic and identified by hpe examination.It is an aggressive malignancy with unfavorable prognosis and a poor ove...
CONNECTION BETWEEN SEIZURE AND SALT
Hyponatremia in the presence of a CNS disease is a known phenomenon . The syndrome of inappropriate ADH secretion – SIADH & Cerebral salt wasting – CSW are two potential causes of hyponatremia in patients with disorder o...
Evaluation of efficacy of sonosalphingogram in evaluating tubal patency with hysterosalphingogram as gold standard
Aim: The objective of present study is to evaluate the efficacy of sonosalphingogram in evaluating patent tubes in infertility patients with hysterosalphingogram as gold standard. Materials and methods: Sonosalphingogr...
A STUDY ON THE CURRENT STATUS OF NEONATAL TRANSPORT TO A SPECIAL NEWBORN CARE UNIT
Introduction: Neonatal care in India has witnessed a revolution in the last 10 years under the auspices of National Rural Health Mission (NRHM). The major causes of neonatal mortality in developing countries are Prematur...
COMPARING THE DIAGNOSTIC ACCURACY OF CT AND USG IN THE DIAGNOSIS OF ACUTE APPENDICITIS
Aim: To evaluate the accuracy of CT and USG in the diagnosis of acute appendicitis in patients who are taken for appendectomy. Study design: Prospective study. Materials and method:Patients who were admitted in the casua...