The impact of altered maternal lipid profile levels on maternal and perinatal outcome in women with Gestational diabetes mellitus
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Context: Gestational Diabetes Mellitus is associated with an increased risk of various short- and long- term adverse maternal outcomes and perinatal outcome. Aims: To identify the impact of altered lipid levels on maternal outcome and neonatal outcomes in women with gestational diabetes mellitus. Settings and Design: Instituitional based study and a prospective case control study. Methods and Material: The fasting lipid profile was taken for about 200 women with Gestational diabetes diagnosed by DIPSI criteria.The patients were divided into two groups based on their lipid profile values. The patient were then followed throughout the antenatal period and the occurance of maternal complications and neonatal complications were studied. Statistical analysis used: Statistical analysis was performed by the student t-test. Results: Among the altered lipid profile group 78.2% of the patients were in age group above 25years,66.7% of patients were in BMI of range 25 to 29kg/m2 .About 41.7% of the patients with altered lipid profile developed Preeclampsia,15.4% had Gestational hypertension,43.6% had polyhydramnios,55.4% had caesarean section .There was about 11.5% macrosomic babies,30.8% babies had respiratory distress syndrome,12.2% babies had hypoglycemia,14.1% of babies had hyperbilirubinemia, 2.6% babies had anomalies,23.7% babies had NICU admissions more than 3 days among the babies born to GDM patients with altered lipid profile. Conclusions: I n o ur s tudy,lipid p rofile a lterations d etected w ere i ncreased t otal c holestral , serum t riglycerides i n GDM patients and lower HDL levels .There was increased incidence of adverse maternal outcome and perinatal outcomes among GDM cases with altered lipid profile .
Authors and Affiliations
Vijaya S, Sudha S
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