Phytochemical and Antimicrobial studies of stembark extracts from Uapaca pilosa (Hutch.)
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 5
Abstract
Objectives: To determine the antimicrobial activity and to also detect the phytoconstituents that are present in the various fractions of the crude extract of Uapaca pilosa. Methods: The antimicrobial and medicinal properties of Uapaca pilosa stembark extracts was examined through phytochemical screening and bioassay on some selected microorganisms: E. coli, S. typhill, S. aureus, B. sbstilis, S. dysenteriae, C. albicans and C. krusei. Result: The preliminary phytochemical screening of the plant extracts were assessed using standard methods. Test for the following active components: alkaloid, anthraquinones, carbohydrate, flavonoids, saponins, glycosides and tanins. All were present. The n-hexane extract show more activity against most of the selected microorganisms than other fractions of the plant extracts measuring clear zones of inhibition of between 10mm and 18mm. but none of the extracts show activity against C. albican and C. krusei. This shows that the bioactive components present in Uapaca proves potency in the treatment of some bacterial infections. Conclusion: the results could justify the use of the plant Uapaca pilosa in traditional herbal medicine for the treatment of bacterial infections.
Authors and Affiliations
Dr. Ayodele J. Atibioke
Keywords
Related Articles
- EP ID EP198439
- DOI -
- Views 88
- Downloads 0
Recombinant DNA technology in drug discovery
Recombinant DNA (rDNA) technology has made a revolutionary impact in the area of human healthcare by enabling mass production of safe, pure and effective rDNA expression products. Constructing a recombinant DNA molecule...
Benzoxazoles: A mini review
Benzoxazoles being structurally similar to bases adenine and guanine interact with biomolecules present in living systems. It can also be used as starting material for other bioactive molecules. This review provides an o...
Effect of Azithromycin and Rosuvastatin on animal models for skeletal muscle relaxant activity in Swiss albino mice
The objective of the study was to evaluate the effect of Azithromycin and Rosuvastatin on animal models for skeletal muscle relaxant activity in Swiss Albino Mice by using Rotarod and actophotometer. Statins affect skele...
A Study on Outcome of Surgical Management of Proximal Humerus Fractures
Fractures of the proximal humerus represent approximately 4% of all fractures and 26% of humerus fractures. The study is to Study the occurrence, mechanism of injury and displacement of various types of fracture accordin...
Effect of the polyherbal cream of Andrographis paniculata and Vernonia amygdalina in Truama wound
To evaluate the wound healing benefits of Andrographis paniculata (AP) and Vernonia amygdalina (VA) as a poly-herbal cream, using shear butter as the oil phase. Excision wound was inflicted on Wistar albino rats which we...