Phytochemical and Antimicrobial studies of stembark extracts from Uapaca pilosa (Hutch.)

Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 5

Abstract

Objectives: To determine the antimicrobial activity and to also detect the phytoconstituents that are present in the various fractions of the crude extract of Uapaca pilosa. Methods: The antimicrobial and medicinal properties of Uapaca pilosa stembark extracts was examined through phytochemical screening and bioassay on some selected microorganisms: E. coli, S. typhill, S. aureus, B. sbstilis, S. dysenteriae, C. albicans and C. krusei. Result: The preliminary phytochemical screening of the plant extracts were assessed using standard methods. Test for the following active components: alkaloid, anthraquinones, carbohydrate, flavonoids, saponins, glycosides and tanins. All were present. The n-hexane extract show more activity against most of the selected microorganisms than other fractions of the plant extracts measuring clear zones of inhibition of between 10mm and 18mm. but none of the extracts show activity against C. albican and C. krusei. This shows that the bioactive components present in Uapaca proves potency in the treatment of some bacterial infections. Conclusion: the results could justify the use of the plant Uapaca pilosa in traditional herbal medicine for the treatment of bacterial infections.

Authors and Affiliations

Dr. Ayodele J. Atibioke

Keywords

Related Articles

Prevalence, severity and clinical characteristics of Molar- incisor hypomineralization in and around Tirupati, AP among 8 to 15 year old children

Developmental disorders of teeth are the problems that are mostly seen in pediatric dentistry, especially on first permanent molars and incisors .Molar incisor hypomineralization (MIH) is the proposed term for this pheno...

Purification and Structure Elucidation of Potential Cytotoxic Agents from Streptomyces parvus KJ623765

Fermentation of Streptomyces (S.) parvus (accession code KJ623765), a locally isolated Streptomyces strains from Egyptian soil sample, was carried out in a 14 L laboratory fermentor. The optimum fermentation conditions w...

Evaluation of Knowledge, attitude and practice about antihypertensive drug use in hypertensive patients in a tertiary care teaching hospital

Context: Hypertension can be controlled through both non pharmacological and pharmacological treatment. Prevention plays significant role in controlling this disease which is achieved by increasing the knowledge and awar...

Preliminary evaluation of antinociceptive and anti-inflammatory activities of petroleum ether extracts of Butea monosperma (L.) leaves in laboratory animals

The petroleum ether extract of the leaves of Butea monosperma was investigated for its antinociceptive and anti-inflammatory activity in respective animal models. In the present study leaves were extracted successively t...

Thorium and uranium in vegetables and fruits from a high background radiation region – along the south west coast of India

The concentration of natural radionuclide (238U, 232Th and 40K) in the soil samples and vegetables were determined in the High background radiation areas – along the South West Coast of India by gamma spectroscopy with N...

Download PDF file
  • EP ID EP198439
  • DOI -
  • Views 76
  • Downloads 0

How To Cite

Dr. Ayodele J. Atibioke (2016). Phytochemical and Antimicrobial studies of stembark extracts from Uapaca pilosa (Hutch.). World Journal of Pharmaceutical Sciences, 4(5), 200-204. https://europub.co.uk/articles/-A-198439