PHYTOCHEMICAL STUDY AND EVALUATION OF ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF VITEX DONIANA SWEET (VERBENACEAE)
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 3
Abstract
Owing to difficulties encountered in the use of synthetic antioxidants, research is moving more and more towards natural antioxidants particularly those from plants. It is in this context that we were interested Vitex doniana Sweet, a plant commonly used in the Ivorian pharmacopoeia for the treatment of several diseases. After an experimental study on a phytochemical screening of the methanolic extract of the plant, a quantitative estimate of total polyphenols (by the Folin-Ciocalteu method) and total flavonoids (by the method aluminum trichloride) was performed. Then; the antioxidant activity of the extract was evaluated through three methods: the method of DPPH (2.2 diphenyl picrylhydrazyl 1), the FTC (ferric thiocyanate) method and TBARS (thiobarbituric acid) method. The results obtained are shown the presence of various compounds including polyphenols groups. Furthermore, inhibition of DPPH radical coupled to the inhibition of lipid peroxidation by test FTC and the TBARS showed significant antioxidant activity for this extracted with a percent inhibition of 53% recorded by FTC and 52% by TBARS. The antioxidant activity of the observed plant would be partly due to its abundance of polyphenols.
Authors and Affiliations
Dr. Ouattara Lacinan
Keywords
Related Articles
- EP ID EP672880
- DOI -
- Views 170
- Downloads 0
MAGIC MUSHROOM A POTENT HALLUCINOGEN: A CRITICAL REVIEW
Hallucinogen, the substance which can alter a person's perception of reality. Some naturally occurring substances proved their potential to act as a hallucinogen. Amongst, Psilocybin (4-phosphorylox-N, N-dimethyltryptami...
PROTECTIVE PROPERTIES OF ETHANOLIC EXTRACT OF PERSIA AMERICANA SEED ON THE OVARY OF POTASSIUM ALUMINIUM SULPHATE INDUCED TOXICITY IN FEMALE WISTAR RATS
Introduction: Potassium aluminium sulphate is a toxic chemical commonly used in the purification of water. This is an old method of water purification but it is still common in some parts of West Africa. This study evalu...
EVALUATION OF NITRIC OXIDE RADICAL SCAVENGING ACTIVITY OF A HEALTH SUPPLEMENT, HERBALONE
Nitric oxide (NO) plays a key role in the production of reactive nitrogen species (RNS). The objectives of this study were to determine antioxidant activities of ethanol extracts of raw materials and product samples were...
SYNTHESIS AND CHARACTERIZATION OF CO-POLYMER AND SUBSTITUTED WITH AMINO DRUG
In this research the structural modification of starch was carried out with methyl nadic anhydride (H) as a spacer by using ceric ammonium nitrate (CAN) as an initiator, and grafted copolymer was substituted with amino d...
EFFECT OF ALCOHOL ON URIC ACID LEVELS AMONG SUDANESE PEOPLE
Background: Several metabolic changes occurs in human's body due to alcoholic consumption which may lead to changes in biochemical substance such as uric acid. Objective: The aim of this study is to evaluate serum uric a...