Plasma Selenium Level based on Dietary Intake in Geriatric Clinic Population at Dr. Hasan Sadikin General Hospital Bandung

Journal Title: Pharmacology and Clinical Pharmacy Research - Year 2016, Vol 1, Issue 1

Abstract

Low plasma selenium level was associated with the increasing risk of death in geriatric patients, particularly those with multiple comorbidities. The sufficient level of selenium intake as an antioxidant is necessary for this population. This study aimed to investigate the plasma selenium level based on dietary intake in geriatric clinic population at Dr. Hasan Sadikin General Hospital Bandung.This study was a descriptive study using cross-sectional method. Fourteen geriatric patients were selected by consecutive sampling technique. Semiquantitative food frequency questionnaire (SQ-FFQ) was used as a tool to assess dietary intake. Plasma selenium level was measured as selenium binding protein 1 (SELENBP1) using enzyme-linked immunosorbent assay kit. Overall, mean of plasma selenium level of the subjects was 2,68 μg/L and mean of selenium intake was 62,85 μg/day. Selenium level of the subjects with sufficient selenium intake (85,7%) was 2,62 μg/L and selenium level of the subjects with deficient selenium intake (14,3%) was 3,05 μg/L.Plasma selenium level of the subjects with sufficient selenium intake was lower if compared with the subjects with deficient selenium intakes.

Authors and Affiliations

Ika M. Silviana, Nuraini Yasmin, Ronny Lesmana

Keywords

Related Articles

Hepatotoxicity Effects of Alcohol Consumption during Paracetamol Therapy of Malaria Patients

The risk of paracetamol induced hepatotoxicity could increase with alcohol consumption. Paracetamol was usually given to tropical malaria patients to treat fever. The aim of this study was to determine the hepatotoxicity...

Predictor of Diabetes: Correlation between Leucine Concentration and Insulin Resistance

Leucine catabolism changes among people with central obesity. This condition can lead to metabolic pathway disorder and increased mTORC-1 activation. Downstream signal of mTORC-1 is p70S6K1, which causes phosphorylation...

Prediction of Binding Mode of Secondary Metabolites in Apium graveolens to Bcl-2

Developing new cytotoxic agent which has minimal effect against normal cell is required to reduce the side effects obtained from the existing chemotherapy agents. Celery (Apium graveolens) showed several pharmacology act...

Diabetes Patients Perceptions on Drugs Consultation Program by Pharmacists

Drugs consultation by pharmacist is an important service to improve the quality of medication use in patients with type 2 diabetes mellitus (T2DM). Perception of patients regarding this service is very useful to boost ph...

Anti-proliferative Activity of Crotalaria pallida Aiton on MCF-7 Breast Cancer Cells

Crotalaria pallida Aiton (C. pallida Aiton) is empirically used as dietary supplement to treat cancer by the people of North Sulawesi. However, its scientific pharmacology activity has not been explored yet. Therefore, t...

Download PDF file
  • EP ID EP352031
  • DOI -
  • Views 148
  • Downloads 0

How To Cite

Ika M. Silviana, Nuraini Yasmin, Ronny Lesmana (2016). Plasma Selenium Level based on Dietary Intake in Geriatric Clinic Population at Dr. Hasan Sadikin General Hospital Bandung. Pharmacology and Clinical Pharmacy Research, 1(1), 11-18. https://europub.co.uk/articles/-A-352031