Pleomorphic adenoma of minor salivary glands of the palate – clinical and histopathological aspects of the tumour
Journal Title: Journal of Stomatology (Czasopismo Stomatologiczne) - Year 2015, Vol 68, Issue 3
Abstract
Pleomorphic adenoma (PA) is the most common benign neoplasm of salivary glands. Although it occurs mostly in major salivary glands, it may also occur in minor salivary glands. Salivary glands of the hard palate are the most common location of minor salivary glands PA. The tumour usually presents as a painless, firm swelling covered with normal mucosa. Development of the tumour takes years. It exhibits wide cytomorphological and cytoarchitectural diversity. The main feature is presence of both epithelial and myoepithelial cells in stroma with variable characteristics. Three types of PA are distinguished: classic (equal qualitative cell to stroma ratio), cell- rich and stroma-rich. Histological composition may influence clinical features of the tumour, such as firmness, elasticity and size. The objective was to present relationship between clinical features of PA and histopathological findings. Assessment included three clinical cases of patients with diagnosed PA of minor palatal salivary glands. In all patients surgical excision of the tumour with normal tissue margin was performed. Two cases presented classic sub-type PA. One case was cell-rich subtype PA. Classic and stroma-rich subtypes of PA grow to bigger sizes than the cell-rich subtype and are more firm and elastic. This is due to the presence of hyaline, cartilage and even bone tissue in the stroma. The cell-rich subtype achieves smaller sizes and is less firm and elastic. Risk of malignant change is found to be higher in the cell- rich subtype. Histological picture has an impact on clinical features of the tumour. Treatment of choice is radical removal of the neoplasm.
Authors and Affiliations
Wojciech Popowski, Rafał Pokrowiecki, Małgorzata Kubicka- Pertkiewicz, Szymon Frank, Andrzej Wojtowicz
Keywords
Related Articles
- EP ID EP77032
- DOI 10.5604/00114553.1165617
- Views 74
- Downloads 0
Treatment of mandibular fractures – review of methodsfrom antiquity to the present
Introduction: A variety of injuries have always accompanied the progress of civilization, consequences of which people had to deal with. Aim of the study: To describe procedures in the treatment of fractures of the lower...
Leczenie endodontyczne zębów z zakrzywionymi kanałami
Wprowadzenie. Leczenie endodontyczne zakrzywionych kanałów korzeniowych jest zwykle trudnym i czasochłonnym zabiegiem, podczas którego może dojść do wielu powikłań. Aby uniknąć niepowodzeń, należy stosować odpowiednie in...
Naczyniaki krwionośne i malformacje naczyniowe w obrębie jamy ustnej – diagnostyka, różnicowanie, leczenie
Wprowadzenie. Naczyniak krwionośny (łac. haemangioma) i malformacje naczyniowe (łac. angioma arteriovenosum) głowy i szyi są schorzeniami często spotykanymi w praktyce stomatologicznej. Zmiany te wywodzą się z układu nac...
Central Giant Cell Lesion of the Maxilla. Case Study
Introduction: Central Giant Cell Granuloma is a benign tumor detected mainly in the lateral segment of the mandible in children and adolescents. Although in most cases this lesion is benign, 20-40% of cases may be clinic...
Commentary on the fifth part of “Dental Clinical Guidance. Prevention and treatment of dental caries in children”
The commentary on the last part of “Dental Clinical Guidance. Prevention and treatment of dental caries in children” emphasizes the necessity of following the rules of directing a child to a consultation or medical tre...