Polydopamine for Biomedical Application and Drug Delivery System
Journal Title: UNKNOWN - Year 2018, Vol 8, Issue 8
Abstract
The aim of this paper is to evaluate the properties of polydopamine and its application in medicine and pharmacy. A dark brown-black insoluble biopolymer produced by the autoxidation of dopamine is polydopamine (PDA), also for applications involving surface modifications it is a bioinspired material with tremendous potential. There has been a rapid increase in the synthesis and applications of polydopamine nanostructures in biomedical fields such as drug delivery, cancer diagnosis and etc., however, there are still vague points in its structure and polymerization mechanism. In this review, it can be said that we have provided a general overview of the recent advances in the dopamine-based material which its application is more in the field of drug delivery and cancer diagnosis. The review starts with a summary of the physicochemical properties of dopamine-based materials and nanocomposites in general. Then in the next step, the detailed description is followed on their applications in the fields of cancer diagnosis, drug delivery, and biomolecule immobilization. Through this review, we hope to promote PDA and its role in medicine and pharmacy becomes more prominent.
Authors and Affiliations
Seyyed Mojtaba Mousavi, Maryam Zarei
Keywords
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