Post operative Nausea Vomiting (PONV):A Clinical Study of Role of Ondansetron and Metoclopramide
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: One of the sequence of anaesthesia is the post operative nausea and vomiting. nausea and vomiting post operative period is not only unpleasant and distressing,but a major factor in upsetting post operative convalescence. Hence the study was done to ascertain the role of ondansetron and metoclopramide in post operative nausea and vomiting,and their compararive efficacy in smoothening convalescence. Material and Methods: Prospective double blind randomized study was planed after institutional ethical committee clearance, 160 patients belonging to ASA class 1 and 2, and scheduled for general surgeries under general anaesthesia, were randomized into 4 (four)groups equally of 40 each, divided as placebo group, ondansetron 4mg, ondansetron 8mg and metoclopramide 10mg groups.The study drugs were given just prior to extubation and all parameters were noted. Statistical analysis was done by χ2 test i.e fourfold or 2x2 contigency table. Results: Ondansetron group showed less amount of PONV compared to metoclopramide group.their were no significant difference between ondansetron 4mg and 8 mg. female gender showed more incident of PONV.
Authors and Affiliations
Anjana Hazarika, Jyotishmoy Bora, Jyotimoni Deori, Pradip Kumae Tiwari, Ranu Shukla
Keywords
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