Post operative pain relief in lower abdominal and lower limb surgeries using fentanyl and tramadol – a comparative study
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 5
Abstract
Introduction: This clinical study is being done to compare and evaluate the drugs, Bupivacaine 0.5% heavy, Tramadol with Bupivacaine 0.5% heavy and Fentanyl with Bupivacaine 0.5% heavy, for Postoperative Pain Relief in Lower Abdominal and Lower Limb surgeries. Methodology: 90 patients were given either of the three sets of intrathecal drugs randomly so that each group comprised 30 patients. Group A- 3ml (15mg) Bupivacaine 0.5% heavy, Group B-3ml (15mg)Bupivacaine 0.5% heavy and Tramadol hydrochloride 25mg (0.5 ml),Group C-3ml (15mg) Bupivacaine 0.5% heavy and Fentanyl citrate 25mg (0.5 ml). Observation: On intergroup comparison the difference is statistically highly significant for duration of sensory blockade. Though duration of sensory blockade is prolonged with both Tramadol and Fentanyl, it is more prolonged with Fentanyl. Conclusion: The mean duration of postoperative pain relief was significantly longer in the range of 6.15±1.02 hours with intrathecal Fentanyl when compared to 4.21±0.91 hours with intrathecal Tramadol. Intraoperative and postoperative vital parameters are not affected by the addition of Fentanyl or Tramadol to Bupivacaine for subarachnoid block. Fentanyl or Tramadol given intrathecally with Bupivacaine does not affect the characteristics subarachnoid block. Thus it can be concluded the Fentanyl in a dose of 25 g intrathecally provides longer postoperative pain relief compared to intrathecal 25mg Tramadol with appreciable less incidence of side effects.
Authors and Affiliations
Ashwini Kumar Patel, Sugandha Sirohi, Ajay Vatal, Dhruvendra Pandey
Keywords
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