Predicting the Renal Outcome and Correlation of Renal Parameters in IG-A Nephropathy using new Oxford-Mest Classification System
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction: IgA nephropathy is the most common primary glomerulonephritis worldwide. It is defined as the glomerular disease with IgA-dominant or co-dominant mesangial immunoglobulin deposits, excluding lupus nephritis. Study aimed to assess the Prognosis of IgA Nephropathy by NEW OXFORD MEST scoring system and to assess the correlation of Mean Arterial Pressure, Serum Creatinine, Glomerular Filtration Rate and Proteinuria with MEST score Material and Methods: Retrospective study reported which was conducted on IgAN patients using the Oxford-MEST classification system. Results: Baseline Creatinine Clearance is a statistically significant individual predictor of disease Outcome. Mean total MEST score of Non Progressors and Progressors was 2.12 and 3.16 respectively. MEST score was higher in patients with Serum Creatinine >1.6 mg/dl in both Non-Progressor and Progressor group. Conclusion: Tubular atrophy (T score in MEST) and Partial Crescents are individually predicting the Renal Survival. MEST score is not superior in predicting the Renal Outcome when compared to Creatinine Clearance and Nephrotic proteinuria.
Authors and Affiliations
V. Kannan Bhaba, V. Balaraman, C. Ilango, Vasudevan . , Heber Anandan
Keywords
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