PREPARATION AND EVALUATION OF BIODEGRADABLE ALBUMIN MICROSPHERES OF KETOROLAC TROMETHAMINE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
The objective of the present study is to prepare sustained-release ketorolac tromethamine microspheres of bovine serum albumin in different ratios by the emulsion cross-linking method using epichlorohydrin. The prepared microspheres were subjected to various physicochemical evaluation and in vitro release studies. The drug release from microspheres of 1:5 ratios is the most constant and prolonged drug release is diffusion followed by erosion. The characteristics of the prepared microspheres are conducive to the formulation of the sustained release drug delivery system.
Authors and Affiliations
Manoj Mishra , Vipan Kamboj , Prabhakar Verma , Vijay Nigam
FLOATING DRUG DELIVERY SYSTEM - CHRONOTHERAPEUTIC APPROACH
The purpose of writing this review on the floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. FDDS is one o...
ASSESSMENT OF LIFESTYLE-RELATED RISK FACTORS CONTRIBUTING FOR CHRONIC NON COMMUNICABLE DISEASE IN PATIENTS VISITING RURAL TERTIARY CARE HOSPITAL
Chronic Non-communicable diseases remain an area of high public health concern especially in developing countries where growing middle class and ever changing lifestyle have led to the rapid increase in the burden of non...
AUGMENTING POTENTIAL ANTIFUNGAL ACTIVITY OF GANDHAKA RASAYANA (A SIDDHA COMPOUND) USING GREEN SYNTHESIZED SILVER NANOPARTICLES FROM COUROUPITA GUIANENSIS LEAF EXTRACT AGAINST SELECTED PATHOGENIC STRAINS
In the present study, augmented antifungal activity of Gandhaka Rasayana in the presence of biosynthesized silver nanoparticles against selected Candida spp. has been demonstrated. Silver nanoparticles were biologically...
CHEWABLE LOZENGE FORMULATION- A REVIEW
Development of lozenges dated back to 20thcentury and is still remain popular among the consumer and hence it has continued commercial production. Lozenges are palatable solid unit dosage form administrated in the oral c...
FORMULATION AND EVALUATION OF SELF PORE FORMING OSMOTIC TABLETS OF GLIPIZIDE
The purpose of this study was to formulate and evaluate self pore forming osmotically controlled drug delivery system of Glipizide. Glipizide is an oral hypoglycemic agent which belongs to BCS class II with relatively sh...