Preparation quality control and clinical application observation of pooled platelets with leukocytes reduced
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 11
Abstract
Objective To investigate the preparation quality and clinical application effect of pooled platelets with leukocytes reduced. Methods The quality and clinical effect of the buffy-coated method prepared pooled platelets leukocytes reduced (experimental group, n=40) and apheresis platelets leukocytes reduced (control group, n=40) were compared. Results The platelet volume (mL), platelet count (×1011), red blood cell contamination (×108) and residual white blood cell (×106) of the experimental group and control group were 278.90±7.92 vs 276.52±8.01, 2.66±0.09 vs 2.66±0.83, 0.54±0.42 vs 0.83±0.84, 0.29±0.54 vs 0.27±0.51, respectively, with no significant difference. The results of bacterial culture were negative, all met the requirements of relevant national standards. In addition, the CCI (×103, 24 h) and PPR (%) were 15.11±9.86 vs 14.61±12.55 and 54.23±18.70 vs 61.41±19.09 respectively, with no significant difference, indicating a certain degree of therapeutic effect. Conclusion The quality and clinical therapeutic effect of pooled platelets leukocytes reduced were consistent with that of apheresis platelets leukocytes reduced.
Authors and Affiliations
Min GUO, Jianmin LI, Jianhui LIU, Ning YANG, Jing ZHANG, Yuqiu LI, Fei CHENG, Xuzhi LIU, Qiang HE, Miao HE, Wenjuan YANG
Keywords
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- EP ID EP738693
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.11.013
- Views 49
- Downloads 0
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