Prescription pattern of fixed dose drug combination in psychiatry out-patient department
Journal Title: Medpulse International Journal of Pharmacology - Year 2018, Vol 8, Issue 1
Abstract
Background: Fixed dose combinations are one of the strategies to reduce the number of drugs prescribed and improve medical compliance. Increased requirement of drugs in patients with more than one disease justifies the use of FDCs. Aim: To examine the prescription pattern of fixed dose drug combination in psychiatry out-patient department. Material and Methods: In this cross-sectional, observational study, 700 prescriptions of psychiatric outpatients which fulfilled the inclusion criteria were evaluated. Prescription was collected by an independent person by clicking its picture with mobile phone outside the OPD without the knowledge of prescriber to avoid any bias. Results: Fixed dose combinations were prescribed in 68 (9.71%) prescriptions. Psychotropic fixed dose combinations were prescribed in 56 (8.0%) prescriptions. Combination of trifluoperazine + chlorpromazine + trihexyphenidyl was prescribed in 23.21% prescriptions, followed by pregabalin + methylcobalamin and escitalopram + clonazepam in 16.07% each. Conclusion: A sound scientific basis should be there to prescribe FDCs, these can be tailor-made according to local needs, thereby reducing adverse drug reactions and financial burden substantially.
Authors and Affiliations
Rashmi Sharma, Brij Mohan Gupta, Rakesh Banal
Keywords
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