Prevalence and Correlation Rates of Urinary Tract Infections in Type 2 Diabetes - A Cross Sectional Study

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Prevalence and Correlation Rates of Urinary Tract Infections in Type 2 Diabetes - A Cross Sectional Study

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 12

Abstract

Abstract: An association between urinary tract infection (UTI) and diabetes mellitus was first noted in an autopsy series in 1940's. Many autopsy studies have shown an increased prevalence of urinary tract infection in diabetics. Animal studies have demonstrated the greater susceptibility of diabetic groups than non-diabetic group to bacteriuria and pyelonephritis. However clinical studies to assess prevalence of bacteriuria in diabetics have showed varied results. Many studies have shown an increased prevalence of bacteriuria in diabetics whereas almost equal numbers of studies have failed to show a significant association. Objective was to study the Urinary tract infection in patients suffering from Diabetes Mellitus. 50 patients suffering from diabetic, who were admitted in tertiary care hospital, were chosen for the study, for a period of one year from January 2016 to December 2016. All the patients had a history of diabetes or with fasting venous blood glucose value equal, or more than 126mg/dl and post prandial blood sugar more than or equal to 180mg/dl and clinical and microbiological features of urinary tract infections, were included in the study. Of the 50 known cases of diabetes choosen for the study, with clinical or microbiological evidence of urinary tract infection, there were 57 (57%) patients who had no evidence of bacteruria, and 43 (43%) patients had bacteruria (positive urine culture from mid-stream urine). In the present study out of 50 diabetic patients’ 28 cases found to be suffering from urinary tract infection.In this study totally 17 diabetic patients was found to be suffering from urinary tract infection. So bacteruria is more common in female than male diabetics. In the present study, the symptoms like fever, dysuria, urgency, frequency, and hematuria, were statistically significant in bacteruric patients when compared between non-bacteruric patients. Predominant bacteria isolated were E.Coli (18) and the next common being Klebsiella (7). Other organisms isolated included were Enterococci (1), and Pseudomonas (1). Candida was isolated along with klesiella in three of the patients. Gender based evaluation of the causative organism also showed E.Coli as the most common cause organism in females. The mean specific gravity was 1.0356 (SD ±0.0204) for bacteruria and 1.027 (SD ±0.0185) for non –bacteruric patients. The study results indicate that bacteriuria and UTI occur more commonly in women with diabetes than in women without disease. The most significant conclusion the study highlighted was that majority of the diabetic patients (60%) suffering from symptomatic UTI were having bacteriuria. The study revealed that the duration of type 2 diabetes patients of more than 10yrs had high predilection for development of UTI's.

Authors and Affiliations

Dr. Vgurudatta Murthy

Keywords

EP ID EP479699
DOI -
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