PREVALENCE AND RISK FACTORS OF GASTROESOPHAGEAL REFLUX DISEASE (GERD) IN ADULT KASHMIRI POPULATION
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 10, Issue 8
Abstract
Objective: The study was conducted with the objective of studying the prevalence of gastroesophageal reflux disease (GERD) and to study various factors associated with it in adult Kashmiri population.Methods: It was a community based prospective cross-sectional observational study conducted by the Department of Medicine and Gastroenterology, GMC Srinagar over a period of 24 mo upon native Kashmiris from urban as well as rural areas as a study group. A total of 2600 subjects above the age of 18 y were studied and the overall prevalence of disease was calculated and also the associated (risk) factors were looked for.Results: The overall prevalence of 20.3% was seen in the study population with female gender being more prone to the development of disease (p<0.001). Other factors of greater significance included body mass index (BMI), smoking, physical activity, intake of spicy foods, posture after meals, dinner to sleep time, non-steroidal anti-inflammatory drug (NSAID) intake and some underlying ailments like asthma and history of abdominal surgery.Conclusion: The overall prevalence of GERD in Kashmiri community is 20.3% with females being more prone with a definite role of factors like BMI, smoking, physical activity, posture after meals, dinner to sleep time interval, intake of spicy foods, drugs and also the co-morbidities.
Authors and Affiliations
Rakesh Kumar Koul, Shagufta Parveen, Padma Lahdol, Prof Samia Rasheed, Nisar A. Shah
GENOTYPE AND ABO BLOOD GROUP ASSOCIATION WITH PREVALENCE OF MALARIA AMONG PATIENTS IN UNIVERSITY OF NIGERIA MEDICAL CENTER: A CROSS-SECTIONAL EVALUATION
Objective: The aim of this study was to evaluate the prevalence of malaria and its relationship with the ABO blood group and genotype at the University of Nigeria Medical Centre. Methods: The study had a prospective cro...
ACTIVITY ANTI-C. TROPICALIS AND EFFECTS OF THE COMBINATION OF (S)-(-)-CITRONELLAL WITH FOUR ANTIFUNGAL APPLIED IN VULVOVAGINAL CANDIDIASIS
Objective: Assess the antifungal potential of the enantiomer (S)-(-)-citronellal [(S)-(-)-CT] isolated and associated to amphotericin B, fluconazole, itraconazole and miconazole against C. tropicalis from vulvovaginal se...
FORMULATION OF KETOCONAZOLE LOADED NANO DISPERSIVE GEL USING SWOLLEN MICELLES TECHNIQUE AND ITS IN VITRO CHARACTERIZATION
Objective: The objective of the present work was to formulate and characterize nano dispersive gel (NDG) for topical delivery of water-insoluble antifungal agent ketoconazole in order to enhance its solubility, penetrati...
TOXICITY OF TAGETES MINUTA ESSENTIAL OIL IN SILVER CATFISH (RHAMDIA QUELEN)
Objective: Evaluation of Tagetes minuta L. essential oil (EOTM) toxicity in the silver catfish Rhamdia quelen.Methods: The EOTM extracted by hydrodistillation was identified qualitatively based on retention indices and t...
MICROORGANISMS AS CHEMICAL FACTORIES FOR ISOLATION OF META-BOLOMES FROM MESOPHILIC SOIL
Objective: To investigate the micro-flora of the mesophilic soil of Rajasthan for isolation of novel compounds having antibacterial potentials.Methods: In present experiments, bacterial colonies were isolated from four d...