PREVALENCE OF NON-FERMENTING GRAM NEGATIVE BACILLI FROM CLINICAL ISOLATES AND THEIR ANTIBIOGRAM PROFILE
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 2
Abstract
Background and Objectives: Non fermenting gram negative bacilli (NFGNB) are an increasing cause of concern in the hospitals as they produce a therapeutic dilemma for the treating physician.The present study was undertaken to know the prevalence and the resistance pattern of non-fermenting gram negative bacilli from clinical isolates. Methods: 2758 bacterial isolates 389 (14.1%) were Non-fermenting gram negative bacilli recovered from various clinical specimens. All the samples were processed for routine bacterial culture and antimicrobial susceptibility test as per standard protocol (CLSI guidelines). Results: Among NFGNBs, 274(70.43%) were Pseudomonas aeruginosa, 99 (25.44%) Acinetobactercalcoaciticus-baumaniicomplex, 10 (2.57%) Acinetobacterlwoffiiand6 (1.54%) Acinetobacterhemolyticus. All the Pseudomonas aeruginosa isolates were sensitive to Polymyxin B and least resistance was observed towards Amikacin 9.85%.All the Acinetobacterisolates were sensitive to Polymyxin B. Only 20.20 % of Acinetobactercalcoaciticusbaumannii complex were resistant to Imipenemwhereas rest all strains were sensitive. Conclusion: The prevalence of NFGNB among clinical isolates was 14.1%. Significantly higher resistance rate was observed by these isolates to almost all the drugs routinely used.
Authors and Affiliations
Thipperudraswamy T. *| Assistant Professor, Department of Microbiology, Basaveshwara Medical College & Hospital Chitradurga, Karnataka, India, Sudhindra. K. S| Associate Professor, Department of Microbiology, Basaveshwara Medical College & Hospital, Chitradurga, Karnataka, India, Shobha Nadigar| Professor and Head, Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India, Mahesh Kumar| Assocate Professor, Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India
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