Prevalence of overt and subclinical thyroid disease in patients tested for thyroid profile in CIMS Bilaspur (C.G.)
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 3
Abstract
Background: Thyroid diseases are common worldwide. In India too, there is a significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid diseases. Thyroid dysfunction has varied impact on pregnancy outcome. Thyroid disorders are amongst the most common endocrine diseases in India. The prevalence and pattern of thyroid disorders depends on sex, age, ethnic and geographical factors and especially on iodine intake. A high iodine intake is associated with lower prevalence of goitre and higher prevalence of hypothyroidism. This study was designed to address this question. We undertook this study to provide reference data for TSH, T4 and T3 in women of this region and evaluate their status of thyroid function. Material and Methods: The study was carried out at Department of Biochemistry, Chhattishgarh Institute of medical sciences, Bilaspur (C.G.). The study was conducted on 1100 subjects of age group 15- 65. The thyrotropin, TSH levels of serum samples were analysed using kits (Diagnostic Product Corporation (DPC), LosAngeles, USA) on the I25 GAMA Counter. Serum T3 and T4 were performed using competitive RIA technique and serum TSH was performed using IRMA technique. Result and Discussion: Of the 1100 total subjects in the age range 15–65 years, 24.1% had thyroid dysfunction and 75.9% were euthyroid. The prevalence of thyroid dysfunction in group I, 19% hypothyroid, 5% hyperthyroidism 75.9% euthyroid and in group II, 16% hypothyroidism, 4% hyperthyroid and 79.5 were euthyroid. The finding that a large number of women unknowingly have laboratory evidence of thyroid dysfunction supports the usefulness of screening for early detection. We hope to extend the study to a larger cross section of men and women in this region keeping in mind environmental and etiopathological factors like auto immunity, drugs, Iodine and non-thyroidal illness.
Authors and Affiliations
Vikas Kumar Gupta, Prashant Nigam, S. K. B. Patil
Keywords
Related Articles
- EP ID EP242901
- DOI -
- Views 90
- Downloads 0
A study of serum levels of magnesium and C-Reactive Protein in Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (DM) has emerged as a major public health issue associated with various complications. Patients with metabolic syndrome (MS) have increased risk of developing cardiovascular disease and type 2 di...
Use of dried blood spot as an alternative method to estimate serum triglyceride in field studies
Introduction: Cardiovascular diseases are showing an increasing trend in both developing as well as developed countries. Raised triglycerides is considered as an important risk factor of cardio vascular diseases. Collect...
Normative data of the urinary bone resorption biomarkers for osteoporosis DPD, CTx and NTx among females in Manipur and its correlation with bone mineral density measured by DEXA scan
Introduction Osteoporosis has become a major public health problem affecting more than 100 million people worldwide Standard diagnosis depends on measuring bone mineral density BMD using a dual energy Xray absorptiometry...
Association between Serum Uric Acid Levels and Hypertension: A Retrospective Study
Introduction: Elevated uric acid levels are frequently associated with lifestyle related diseases. Serum uric acid levels also have shown to play a very important role in the development of cardiovascular morbidity and r...
Biochemical Profile of women with pregnancy induced hypertension
Background: Hypertensive disorders complicating pregnancy are common and form one of the deadly triad, along with hemorrhage and infection. Pre-eclampsia is a syndrome of generalized endothelial dysfunction initiated by...