Prevalence of Vitamin-D Deficiency in HIV Positive Patients and its Correlation with Occurrence of Opportunistic Infections and CD4 Counts
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
The vitamin D endocrine system plays an essential role in calcium homeostasis and bone metabolism required for optimal absorption of dietary calcium and phosphate. Apart from role in calcium homeostasis other biological actions include induction of cell differentiation, inhibition of cell growth, immunomodulation and control of other hormonal systems. Several studies have demonstrated low serum vitamin 25(OH)D levels in populations across India. Very high percentage of HIV -infected people live in areas of the world where nutritional deficiencies are also highly prevalent, and the interactions between HIV and nutritional status have been documented. In last few years there have been reports suggesting an increased prevalence of osteopenia and osteoporosis in HIV positive patients 7,8,9. Middle-aged persons with human immunodeficiency virus (HIV) infection are at risk for numerous co-morbidities typically seen including metabolic syndrome, osteoporosis and fractures, insulin resistance, diabetes, cardiovascular disease, cognitive impairment and opportunistic infection .Many of which have also been associated with vitamin D deficiency. HIV infection and exposure to certain antiretroviral might contribute to altered levels of 25(OH) vitamin D.Vitamin D insufficiency or deficiency may increase the incidence of opportunistic infection in HIV patients. Vitamin D level in HIV patients and its co- relation with opportunistic infection and immunological status are not yet well defined. Therefore present study is designed to find the correlation between HIV status and vitamin D levels.
Authors and Affiliations
Dr Sivaprakash Varadan
Keywords
Related Articles
- EP ID EP520053
- DOI -
- Views 38
- Downloads 0
Medications Used Before and After Cataract Surgery in A Tertiary Care Hospital
Introduction: Cataract is the most common ocular disease, which is characterized by opacification of lens resulting in gradual progressive diminution of vision. Drug utilization research contributes to the rational drug...
A Study of Arthroscopic Synovial Biopsy in Chronic Synovitis of Knee Joint
Background: Synovial inflammatory conditions of knee joint is one of the most common non traumatic disorders of knee joint. Diagnosis of synovial inflammatory conditions by advance methods like Arthroscopic guided select...
Neonatal Screening Program, Study of Congenital Hypothyroidism Cases
Introduction: Congenital hypothyroidism is one of the most common preventable causes of mental retardation. The clinical manifestations are so subtle that many newborns are undiagnosed at birth. Aim of study: Studying ne...
Effect of Yoga on the Reduction in Symptoms of Respiratory DisordersCough, Wheezing, Rapid Shallow Respiration
The aim of the study was to find out the effect of yogic exercise and yogic breathing on the reduction of symptoms of respiratory disorders. The researcher have visited a school in which 1100 pupils were studying. All th...
Molecular characterization of Staphylococcus aureus - human pathogen from clinical samples by RAPD markers
Staphylococcus aureus is one of the most significant pathogens causing nosocomial and skin infection. It is an opportunistic bacterium, frequently part of the human micro flora, causing disease when the immune system bec...