Prevention, Screening and Diagnosis of Cervical Carcinoma: A Literature Review
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
The human papillomavirus (HPV) is an unenveloped double stranded deoxyribonucleic acid (dsDNA) virus capable of infecting humans and inducing cervical carcinoma in females. HPVs can also be grouped to high-risk and low-risk HPV types. Low-risk HPV types include types 6, 11, 42, 43, and 44. High-risk HPV types include types 16, 18, 31, 33, 34, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, and 70. HPV16 and 18 have been implicated as the commonest aetiologic agent in this disease. Various methods have been used in testing the presence of human papillomavirus including histology, pap smear, polymerase chain reaction and hybridization technique. Pap has been used for cervical carcinoma screening worldwide. Cervarix and Gardasil are effective vaccines against the human papillomavirus type 16 and 18
Authors and Affiliations
Godstime I. Irabor, Kenneth A. Omoruyi, Dominic Akpan, Ayodele J. Omotoso, Martin A. Nnoli, Edoise M. Isiwele
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