PROCESS OF CONTINUOUS PRODUCTION OF OLIGOAMINOSACCHARIDES IN A COLUMN REACTOR
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2010, Vol 0, Issue
Abstract
A continuous production of oligoaminosaccharides from chitosan was achieved with a column reactor packed with chitosanolytic enzymes-containing mycelia of Mucor circinelloides and Mucor racemosus immobilized in porous carriers. The efficient work of the bed used for chitosan hydrolysis in a column reactor lasted for several or more than 10 days and depended on a type of a carrier and substrate concentration. Because a crucial parameter for large scale applications of enzymes is their operating stability, presented research intended to improve it through stabilization of proteins and elimination of their leakage from the carrier. Cross-linking of mycelial preparations of chitosanolytic enzymes with 1% glutaraldehyde did not increase their stability and further process optimization is necessary.
Authors and Affiliations
Katarzyna Struszczyk, Mirosława Szczęsna-Antczak, Emilia Pomianowska, Łukasz Stańczyk, Justyna Wojciechowska, Tadeusz Antczak
Keywords
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- EP ID EP73711
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