Profile of Anemia in Chronic Kidney Disease Patients at a Rural Tertiary Care Centre: A Prospective Observational Study
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Introduction: Anemia is a very common manifestation among patients of CKD. As the renal dysfunction increases in severity, there is proportional increase in prevalence and severity of haematological impairment. There is increased incidence of cardiovascular dysfunction, cognitive impairment and sleep disturbances in anemic patients with CKD. It is also associated with progression of renal disease and increased mortality. This study was conducted to study the profile of Anemia in Chronic Kidney Disease patients at a rural tertiary care centre in North India. Material and Methods: This prospective observational study was done on 100 patients of CKD taken from Department of Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala. Chronic kidney disease (CKD) was defined as per Kidney Dialysis Quality Initiative (KDOQI) guideline. Results: The mean age of the study population was 52.4 years. The mean Hemoglobin level in our study was 8.39 ± 1.71 g/ dL. The most common profile seen on peripheral blood smear was normocytic normochromic anemia (76%), followed by microcytic hypochromic picture seen 22% patients. Mean Hemoglobin level and RBC indices (MCV, MCH, MCHC) were significantly lower in patients receiving hemodialysis. Conclusion: Anemia is a very common clinical manifestation in patients of Chronic Kidney Disease. Severity of Anemia increases with progressive renal damage. Patients receiving hemodialysis are more anemic as compared to non-dialyzed CKD patients.
Authors and Affiliations
Neha Sundhir, Sandeep Joshi, Chander Mohan Adya, Ruby Sharma, Himani Garg
Keywords
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