Prognostic factors of postoperative patients with intracerebral hemorrhage and application of event-related potentials in consciousness monitoring
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 4
Abstract
[Objective] To explore the risk factors of prognosis of patients with intracerebral hemorrhage at 6 months after operation, and to study the diagnostic efficacy of event-related potential (ERP) on outcome and prognosis. [Methods] Forty postoperative patients with intracerebral hemorrhage were prospectively enrolled. The age, sex, preoperative blood loss and GCS were collected. The mismatch negative wave (MMN) was measured by ERP on the 1st, 3rd, 7th and 14th day after operation, and the modified coma recovery scale (CRS-R) was evaluated simultaneously. The Glasgow outcome scale (GOS) of patients was assessed by telephone follow-up after 6 months GOS 1~2 and 3~5 was defined as poor prognosis and good prognosis., respectively. Multivariate Logistic regression analysis was used to analyze the risk factors affecting the outcome and prognosis of patients, to explore the correlation between MMN and CRS-R, and ROC curve was used to evaluate the predictive value of MMN on the prognosis of patients. [Results] There were significant differences in the preoperative blood loss, admission GCS score and MMN amplitude between patients with good prognosis and those with poor prognosis on the 3rd, 7th and 14th day after operation. Multivariate Logistic regression analysis showed that MMN amplitude on the 14th day after operation was an independent risk factor for poor prognosis (OR=0.100, 95%CI: 0.000~0.355, P<0.05). The amplitude of MMN was strongly correlated with CRS-R and the correlation coefficient was 0.643 (P<0.01). The amplitude of MMN on the 14th day after operation had a high diagnostic efficiency for the clinical prognosis at 6 months. [Conclusion] The lower the amplitude of MMN on the 14th day after operation, the worse the prognosis of patients. ERP monitoring of postoperative disturbance of consciousness in patients with intracerebral hemorrhage is expected to become an effective tool to predict the prognosis of patients.
Authors and Affiliations
Mengmeng HE, Chen CHU, Jianling. GAO
Keywords
Related Articles
- EP ID EP750485
- DOI 10.3969/j.issn.1002-0152.2024.04.002
- Views 31
- Downloads 0
Research progress of neuropsychiatric disorder in pituitary neuroendocrine tumor
This article seeks to delve into the correlation between pituitary neuroendocrine tumors (PitNET) and neuropsychiatric disorders while summarizing the most recent advancements in related research. Some patients with PitN...
Incidence and predictors of early radial artery occlusion associated transradial approach
ObjectiveThis study was to explore factors related to early radial artery occlusion (RAO) associated transradial approach(TRA).MethodsPatients who underwent the TRA from July 2021 to Jan 2024 were included in our study....
Research progress of psychological and biological mechanism of childhood trauma affecting social anxiety disorder
Social anxiety disorder has a significant negative impact on individuals’ social interaction and normal life, and childhood trauma plays an important role in the occurrence and development of SAD. Childhood trauma affect...
Insular involvement after cerebral infarction predicts the risk of cardioembolic stroke
[Objective] To determine whether insular involvement was associated with cardioembolic stroke (CES) in patients with middle cerebral artery (MCA) infarction. [Methods] The patients with MCA infarction admitted to stroke...
The application of fuorescein sodium for the microscopic resection of medulloblastoma
[Objective] To investigate the safety and efficacy of sodium fluorescein-guided microsurgery in children with medulloblastoma, and to analyze the surgical efficacy and prognosis.Among them, 12 cases underwent unilateral...