Progressive increasing of cutaneous leishmaniasis in Kashan district, central of Iran
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 4
Abstract
Objective: To investigate the prevalence of cutaneous leishmaniasis in important endemic focus of Kashan district, central of Iran during 2007-2008. Methods: This was a cross-sectional study and 5 098 individuals were selected from thirteen rural and urban districts of Kashan city. Information of positive cases including age, sex, job, number and sites of ulcers or scars, date and place of the ulcer, and results of clinical examination and laboratory tests were recorded. Diagnoses of affected cases were based on clinical examination and microscopic observation of the ulcer parasite. The results were analyzed with statistical Chi-square test. Results: An infection prevalence rate of 6.4% was obtained among 5 098 individuals. Regarding to 326 affected cases, 103 (2.0%) and 223 (4.4%) persons were observed with active lesion and scars, respectively. The highest frequency of active ulcer rate (23.3%) was associated with age group of 20-29 years old, while the lowest rate was related to age group of 0-9 years old with 7.8% infection. About 49.5% of the infected cases were under 30 years old. This study showed 64.1% of cases with one and the rest of them with two or more ulcers. Hands (46.6%) were the most affected parts of body. Conclusions: There is a progressive increasing of cutaneous leishmaniasis in Kashan district and this is a warning to local health workers to provide prevention as well as control program of the disease.
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Antibacterial and antifungal study ofCichorium intybus
Objective: To elucidate the antibacterial and antifungal activities of Cichorium intybus (C. intybus). Methods: The antibacterial and antifungal activities of C. intybus crude extract and its different solvent soluble fr...
In vitro antiplasmodial activity of marine sponge Clathria vulpina extract against chloroquine sensitive Plasmodium falciparum
Objective: To explore the antiplasmodial potential of marine sponge Clathria vulpina (C. vulpina) against chloroquine sensitive Plasmodium falciparum (P. falciparum). Methods: The marine sponge C. vulpina was collected f...
Molecular typing of Mycobacterium tuberculosis isolates from Yaound é reveals RIF resistance markers, clonal relatedness and mutation patterns
Objective: To understand the spread of drug resistance and identifying diagnostic probes among the local tuberculosis (TB) strains in order to design rational control tools for tuberculosis controls. Methods: TA cloning...
Restorative effect of Eclipta alba in CCl4 induced hepatotoxicity in male albino rats
Objective: To elucidate the restorative effect of the aqueous leaf extract (85%) of the traditional medicinal plant Eclipta alba (E. alba) against CCl4 induced hepatotoxicity in male albino rats. Methods: Restorative act...