Prophylactic effect of Tamsulosin on postoperative urinary retention in men undergoing benign anorectal surgeries
Journal Title: Medpulse International Journal of Surgery - Year 2017, Vol 4, Issue 1
Abstract
Background: POUR is the most common complication of surgery for benign anorectal disease. Tamsulosin, being an alpha-1a receptor blocker acts by reducing tone in bladder outlet, shown as an effective preventive agent of POUR for certain anorectal and inguinal surgeries. Aim: To investigate the prophylactic effect of Tamsulosin on postoperative urinary retention in men undergoing benign anorectal surgeries. Material and Methods: A total of 40 adult cases from both sexes were randomly grouped into Group P (control(given two doses of placebo orally 6 hours before surgery and 6 to 12 hours after surgery) and Group T (Tamsulosin) (given 0.4 mg of tamsulosin orally in the same manner as the placebo).All cases were closely followed for 24 hours postoperatively any voiding difficulties or urinary retention was recorded. Results: The mean prostate volume in Group P and Group T was 29.80 ±7.10 and 33.92 ±4.72 ml respectively. The post-void urinary retention (PVR) <50 ml in patients of Group P and Group T was 68.33% and 71.67% respectively.It was observed that in Group P; 7 (35%) patients had POUR while in Group T, one (5%) patient had POUR after surgery. There was no statistical difference in POUR among two study groups. (P>0.05). Conclusion: Patients in Placebo group had more POUR as compared to Tamsulosin group with statistical difference. Thus, the present study suggests that perioperative Tamsulosin administration reduces the incidence of postoperative urinary retention in men undergoing benign anorectal surgeries
Authors and Affiliations
Syed Nabisab, Sajid Ahmed Mudhol, Afeeya Anjum
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