Pseudo-allergic reactions to tuberculin in cattle
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2018, Vol 32, Issue
Abstract
Introduction. Bovine tuberculosis (TB) is a chronic bacterial disease of cattle and other species of domestic and wild animals. Bovine TB can also infect humans. Delayed hypersensitivity test is the standard diagnostical method of bovine TB. Comparative intradermal tuberculin test using bovine tuberculin and allergen of atypical mycobacteria is applied to differentiate animals infected with M. bovis and those sensitized to tuberculin due to exposure of other types of mycobacteria. Erroneous interpretation of meaning of nonspecific reactions to tuberculin can lead to the slaughtering of productive animals and contribute to spreading of TB. Besides, appearing cases of para-allergic and pseudo-allergic reactions to tuberculin in cattle are not thoroughly studied in Ukraine. The goal of work was to determinate reasons of positive reaction to tuberculin (PPD) in cattle on two farms that are free from TB infection. Materials and methods. Epizootological monitoring, clinical examination of cattle, allergic study with tuberculin for mammals and allergen of atypical mycobacteria (AAM), anatomopathological, bacteriological, biological tests were performed. Results of research and discussion. Results of conducted studies indicated that pseudo-allergic reactions to mycobacterial allergens were caused by dicroceliasis and echinococcus invasion, as well as Aspergillus niger sp. Conclusions and prospects for further research. The presence of invasions in the organism of animals can lead to a false positive result of allergic test for tuberculosis and to the unreasonable slaughtering of productive animals. Thus, it is necessary to conduct monitoring on the presence of parasitic diseases in animals on farms. Moreover, studies of feed contamination with bacterial and fungal microflora are also important because such contaminated feeds cause mycosis in animals and as the result – pseudo-allergic reactions to mycobacterial allergens. Regular disinfection of livestock premises, farm territories and feed storage facilities is important for control and prevention of infectious and invasive diseases of farm animals.
Authors and Affiliations
Andriy Zavgorodnii, Victor Bilushko, Mykola Kalashnyk, Svitlana Pozmogova, Natalia Kalashnyk
Keywords
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- EP ID EP389330
- DOI 10.31073/vet_biotech32(2)-20
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