Pulmonary complications in the course of acute poisoning
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 9
Abstract
Acute poisonings are a common cause of respiratory failure. Respiratory insufficiency in poisoning may be due to causes pulmonary and/or extrapulmonary, depending on the primary or secondary dysfunction of pulmonary compartment and/or mechanical compartment. Respiratory failure in cases of poisoning can be caused by direct toxic effects of poison, may develop secondary to organ damage caused by poison, and can also be a complication of medical procedures performed in poisoned patients. Toxic substances can affect both the pulmonary compartment and mechanically, causing parenchymatous respiratory failure – embolism, manifested by a decrease in oxygenation and/or ventilation failure, disorders resulting from respiratory drive, the strength of respiratory and respiratory mechanics, leading to retention of carbon dioxide system. Substances directly irritating the respiratory tract can include hot air, gases, irritant, toxic hydrocarbons and liquid evaporates easily, which can directly damage the lungs. Paralysis of the respiratory center, or central nervous system depressant effects on the central mechanism promotes ventilation of respiratory impairment. This picture observed in the sleeping drug poisoning, drugs, alcohol, and as end-stage form of any significant toxicity in life. Resulting in dysfunction of motor disorders of the respiratory muscles may be caused by eg organophosphorus compounds, some snake venom, botulinum toxin, tetanus toxin, some fungal toxin, curare. Therapeutic procedure will depend on the rate of exacerbation of respiratory failure and pathomechanism of its formation. Severe respiratory insufficiency is an indication for endotracheal intubation, mechanical ventilation and cross-pharmacological treatment. In extreme situations of impaired gas exchange in the lungs apply highly specialized treatments, such as HBO, or ECMO.
Authors and Affiliations
Iwona Jarocka, Piotr Jakubów, Agata Kulikowska, Magdalena Łukasik-Głębocka, Marzena Wojewódzka-Żelezniakowicz, Agnieszka Borysiewicz, Jerzy Ładny, Sławomir Czaban
Keywords
Related Articles
- EP ID EP53985
- DOI -
- Views 167
- Downloads 0
Cukrzyca i cukrzycowa choroba nerek zwiększający się problem epidemiologiczny
Inwazyjne zakażenia grzybicze u dzieci i młodzieży po przeszczepieniu komórek krwiotwórczych
Wstęp. Pacjenci poddawani procedurze transplantacji komórek krwiotwórczych (HSCT) stanowią grupę, w której ryzyko inwazyjnych zakażeń grzybiczych (IFI) jest szczególnie wysokie. Zakażenia grzybicze są częstą przyczyną ch...
Treatment of length discrepancy and axial deviations of lower extremities after septic osteoarthritis – obstacles, complications, analysis of results
Septic hematogenous osteomyelitis and arthritis in neonates and newborns may be the source of many late complications leading to leg length discrepancies and axial deviations. The destruction of joint structures and espe...
Environmental exposure to tobacco smoke and condition of organ of visio
According to the most recent epidemiological data, nicotine causes a greater number of addiction-related deaths than cocaine, heroin and alcohol combined. Its toxicity also significantly affects the organ of sight.Smokin...
Skuteczność pojedynczej i podwójnej predonacji łącznej z pooperacyjnym odzyskiem krwi w operacjach skolioz
<b>Wstęp.</b> Autotransfuzja jest zalecana u pacjentów podlegających zabiegom chirurgicznym kręgosłupa jako uznany środek redukujący potrzebę transfuzji krwi obcej. Istnieje niedobór badań, kt...