Thromboembolic complications (TEC) in patients with acute leukemias and lymphomas – single center experience
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 9
Abstract
<b>Introduction.</b> Thromboembolic complications (TEC) are common abnormalities in cancer patients and they refere expecially to solid tumours. The pathogenesis of thromboembolic disease in neoplasias is complex and multifactorial. In patients with hematological malignancies may occur some of thromboembolic complications such as: venous thromboembolism (VTE), pulmonary embolism (PE) and disseminated intravascular coagulation (DIC).<br><b>Material and methods. </b>The aim of our study was to analyse the incidence of thromboembolic complications in patients with acute leukemias and lymphomas as well as association between risk factors and development of TEC and effect of TEC on overall survival (OS). The study population included 70 patients with acute leukemias and 65 patients with lymphomas treated in Department of Hematology Medical University Wroclaw, Poland.<br><b>Results.</b> In group of patients with acute leukemias we found thromboembolism complications in 9 patients (12.8%), in group of patients with lymphomas we observed TEC in 8 patients (12.3%). Patients with acute leukemias and VTE were significantly older than patients without thrombotic complications. Moreover, patients associated thrombotic events in acute leukemias with high risk of disease.<br><b>Conclusions. </b>This analysis confirm high incidence of TEC in patients with hematologic malignacies.
Authors and Affiliations
Justyna Dzietczenia, Tomasz Wróbel, Grzegorz Mazur, Aleksandra Butrym, Kazimierz Kuliczkowski
Keywords
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