QUALITY EVALUATION OF MARKETED FORMULATION OF MOUTH DISSOLVING VOGLIBOSE TABLETS
Journal Title: International Journal of Pharmaceutical, Biological and Chemical Sciences (IJPBCS) - Year 2012, Vol 1, Issue 2
Abstract
The main objective of this study was to compare the five brands of mouth dissolving tablets containing voglibose, an antidiabetic. Novel MDT technique provides the patient compliance and also meets the pharmaceutical needs such as improvement in the life cycle management over the convenient dosing especially for paediatrics, geriatric and for psychiatric patients having difficulty in swallowing the conventional tablets and capsules dosage forms. For this study, the mouth dissolving tablets were collected from market and were evaluated for drug content, friability test, hardness test, wetting time, weight variation test, and disintegration and in-vitro dissolution studies.
Authors and Affiliations
V. M Chatur, S. V. Ghodekar, P. M. Kadam, M. P. Ratnaparkhi, S. P. Chaudhari*
A REVIEW OF NOVEL APPROACH IN BILAYER TABLET TECHNOLOGY
Over the past 30 years as the expense and complications involved in marketing new drug entities have increased, with concomitant recognition of the therapeutic advantages of controlled drug delivery, greater attention ha...
RP-HPLC VALIDATION OF RELATED SUBSTANCES OF NEBIVOLOL IN BULK & 2.5/5/10/20 MG TABLETS
A gradient reverse phase HPLC method was developed for the determination of related substances in Nebivolol in bulk and their tablets. The known related substances are Desfuoroimpurity[1-(chroman-2-yl)-2-(2-(6fluorochrom...
IMPROVE ORAL BIOAVAILABILITY OF ACECLOFENAC USING SOLID DISPERSIONS BY DROPPING METHOD
The objective of the present investigation was to study the effect of polyethylene glycol 8000 (PEG 8000) on in vitro dissolution of Aceclofenac from solid dispersions. Initial studies were carried out using physical mix...
DEVELOPMENT AND VALIDATION OF ANALYTICAL TECHNIQUE FOR NON STEROIDAL ANTI INFLAMMATORY DRUGS (NSAIDs) BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)
Drug analysis plays an important role in the development of drugs, their manufacture and therapeutic use. Pharmaceutical industries rely upon quantitative chemical analysis to ensure that the raw material used and final...
QUALITY EVALUATION OF MARKETED FORMULATION OF MOUTH DISSOLVING VOGLIBOSE TABLETS
The main objective of this study was to compare the five brands of mouth dissolving tablets containing voglibose, an antidiabetic. Novel MDT technique provides the patient compliance and also meets the pharmaceutical...