Recent developments in anticancer applications of the Schiff bases and their metal complexes
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2018, Vol 26, Issue 2
Abstract
Metal complexes of Schiff base signify a class of compounds that have become a field of huge interest for chemists all over the world because of their immense therapeutic applications. They show versatile bonding behaviour because of easy variation in steric and electronic structure of Schiff bases by taking appropriate aldehydes/ ketones and amines. This review highlights the up-to-date research on transition metal complexes of Schiff bases emphasizing mainly on their anticancer applications. We present a complete study of structural factors that are responsible for their activity against particular cancer cell lines and the methods used for such study that includ s both experimental and theoretical approach. Contemporary strategies will be helpful to the development of new drugs based on the moiety and interactions with various cancer cell lines which lead to the apoptosis
Authors and Affiliations
Madhuri Chaurasia, Sulekh Chandra
Keywords
Related Articles
- EP ID EP365959
- DOI -
- Views 110
- Downloads 0
Retrospective Study of Eclampsia in a Teaching Hospital
Eclampsia is one of the major cause of both maternal and perinatal mortality in India. Retrospective study of eclampsia was done in our hospital from Jan-2011 to Jun-2013 Over a period of 2 ½ year to know the incidence,...
Leri’s diseases – A rare mesenchymal sclerosing bone dysplasia of right femoral neck
Introduction: Melorheostosis (synonyms: candle bone disease, melting wax syndrome, Leri disease) is a rare chronic bone disorder, first described in 1922 by Leri and Joanny. Men and women are equally affected, and no her...
Study of ovarian function after hysterectomy
Introduction: Hysterectomy is one of the commonest operations performed in the world being second most common surgery in India in reproductive age group. The important concern is impact of hysterectomy on ovarian functio...
Development of indigenous innovative visual reinforcement system for hearing screening among young children
Visual reinforcement audiometry (VRA) is the gold standard hearing assessment procedure. It is a combination of both visual and auditory stimuli uses conventional toys and speakers to estimate hearing. The aim of the stu...
Hereditary Multiple Exostosis - Diaphyseal Aclasis
Hereditary Multiple Exostosis (HME) is an inherited autosomal dominant metaphyseal overgrowth that is characterized by multiple osteochondromas. In 75% cases it occurs before age of 20 yrs with male predominance of 2:1....