Red blood cell storage lesion: a progress review
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 12
Abstract
Red blood cells are the main mediators of oxygen transportation in the body. Under normal conditions, the life span of red blood cells circulating in the human body is approximately 120 days. However, after blood donation, erythrocytes in the storage process will eventually induce the occurrence of storage injury due to the accumulation or consumption of metabolites. This review presents a summary of recent research on the mechanism of red blood cell storage lesion, its potential clinical effects and corresponding strategies as follows.
Authors and Affiliations
Cheng CHEN, Rong XIA
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Objective To investigate the HBV infection of TMA initially reactive but discriminatory test non-reactive samples(NDR) after the individual donation nucleic acid detection(ID-NAT)of TMA, and analyze its serological and m...
Perioperative blood management strategies for elderly orthopedic patients
With the arrival of an aging society, the number of orthopedic geriatric patient who require surgical treatment is also rapidly increasing. Elderly patients have decreased hematopoietic function, and perioperative blood...
HBV infection among blood donors from 18 domestic blood stations of prefecture-level cities
Objective To analyze the hepatitis B virus (HBV) infection data of blood donors from 18 domestic blood stations, so as to investigate the HBV infection situation of blood donors. Methods The positive rate of HBV and its...
Study on the protective effect of rapamycin-treated dendritic cells on transfusion-related acute lung injury after infection
Objective To investigate the viability of rapamycin-treated rapamycin-treated dendritic cells (DCs) in intervening transfusion-related acute lung injury (TRALI) after infection. Methods 1)The TRALI mouse model was induce...
Changes of coagulation function and other indicators of the thawed FFP and FLP at 2-6℃
Objective To observe the changes of coagulation factor activity and protein content of the thawed fresh frozen plasma (FFP) and fresh liquid plasma (FLP) during storage at 2-6℃, and to provide reference for exploring the...