Relation of age, body weight and BMI with bone mineral density (BMD) at spine, proximal femur and total body BMD in postmenopausal Kashmiri women: a study of 165 cases.
Journal Title: JOURNAL OF CONTEMPORARY MEDICINE - Year 2017, Vol 7, Issue 3
Abstract
Aim: To find prevalence of osteoporosis and relation of age, body weight and Body Mass Index (BMI) with Bone Mineral Density (BMD) in postmenopausal Kashmiri women.Methods: Postmenopausal women, attending the outpatient department, were registered for the study after taking a written informed consent. Age, height and weight were recorded for each subject and BMI calculated as kg/m2. BMD (t-score) was obtained at lumbar spine, proximal femur and whole body using Dual Energy X-ray Absorptiometry (DEXA). The subjects were divided into groups based on age, weight, BMI, and BMD (t-score). The results were analyzed using statistical package for social sciences. Results: 165 postmenopausal Kashmiri women with a mean age of 58.9 ± 9.7 years, mean weight of 56.5 ± 11.7 kg and mean BMI of 24.1 ±4.3 kg/m2 were analyzed. 96.4 %, 64.3% and 68.5 % subjects had low bone mass (osteopenia and osteoporosis) at lumbar spine, proximal femur and total body respectively. Prevalence of osteoporosis at all the sites was more in advanced age groups which was statistically significant (P < 0.05). Both body weight and BMI on a higher side had a protective influence against osteoporosis which was statistically significant (P < 0.05) except for BMI and BMD at lumbar spine (P = 0.276). Age had a negative correlation with BMD at all the measured sites (P < 0.00001) while as body weight and BMI had a positive correlation (P < 0.00001).Conclusion: Nearly 80 % of Kashmiri postmenopausal women are osteoporotic at the lumbar spine. While as only one fourth’s are osteoporotic with respect to total body BMD and only one fifth’s with respect to proximal femur BMD. With increasing age BMD decreases at all the sites. Increase in body weight and BMI have a protective role against osteoporosis with exception of lumbar spine where BMI is not protective. Body weight is a better predictor of BMD than BMI at all the sites.
Authors and Affiliations
Naseer Ahmad Mir
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